6 Human T-cell leukaemia virus

G Franchini, H Streicher - Baillière's clinical haematology, 1995 - Elsevier
HTLV-I has a complex and finely regulated mechanism of replication, which can be used as
a model to study both cellular and viral regulation pathways in T-cells. Understanding of the …

Role of wild-type and recombinant human T-cell leukemia viruses in lymphoproliferative disease in humanized NSG mice

DD Huey, B Bolon, K La Perle, P Kannian… - Comparative …, 2018 - ingentaconnect.com
Chronic infection with human T-cell leukemia virus type 1 (HTLV1) can lead to adult T-cell
leukemia (ATL). In contrast, infection with HTLV2 does not lead to leukemia, potentially …

HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells

N Araya, T Sato, H Ando, U Tomaru… - The Journal of …, 2014 - Am Soc Clin Investig
Human T-lymphotropic virus type 1 (HTLV-1) is linked to multiple diseases, including the
neuroinflammatory disease HTLV-1–associated myelopathy/tropical spastic paraparesis …

Immunopathogenesis of HTLV-1-assoaciated myelopathy/tropical spastic paraparesis (HAM/TSP)

HT Fuzii, GA da Silva Dias, RJS de Barros, LFM Falcão… - Life sciences, 2014 - Elsevier
Human T-cell lymphotropic virus type 1 (HTLV-1) is associated with adult T-cell
leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis …

Double control systems for human T‐cell leukemia virus type 1 by innate and acquired immunity

M Kannagi, A Hasegawa, S Kinpara, Y Shimizu… - Cancer …, 2011 - Wiley Online Library
Human T‐cell leukemia virus type 1 (HTLV‐1) is the causative retrovirus of adult T‐cell
leukemia (ATL) and HTLV‐1‐associated myelopathy/tropical spastic paraparesis …

Distinct transformation tropism exhibited by human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 is the result of postinfection T cell clonal expansion

P Kannian, H Yin, R Doueiri, MD Lairmore… - Journal of …, 2012 - Am Soc Microbiol
Human T lymphotropic virus type 1 (HTLV-1) and HTLV-2 are related but pathogenically
distinct viruses. HTLV-1 mainly causes adult T cell leukemia, while HTLV-2 is not associated …

HTLV-1-infected thymic epithelial cells convey the virus to CD4+ T lymphocytes

LRC Barros, L Linhares-Lacerda, K Moreira-Ramos… - Immunobiology, 2017 - Elsevier
The human T-lymphotropic virus type-1 (HTLV-1) is the causative agent of adult T cell
leukemia/lymphoma (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis …

T-cell control by human T-cell leukemia/lymphoma virus type 1

G Franchini, R Fukumoto, JR Fullen - International journal of hematology, 2003 - Springer
Human T-cell leukemia/lymphoma virus type 1 (HTLV-1) causes neoplastic transformation of
human T-cells in a small number of infected individuals several years from infection …

A novel therapeutic molecule against HTLV-1 infection targeting provirus

A Tanaka, S Takeda, R Kariya, K Matsuda, E Urano… - Leukemia, 2013 - nature.com
Human T-cell leukemia virus type I (HTLV-1) is a retrovirus that causes adult T-cell leukemia
(ATL) and the neurological disorder, HTLV-1-associated myelopathy, in humans. 1–3 HTLV …

The genetic background as a determinant of human T-cell leukemia virus type 1 proviral load

T Nitta, M Tanaka, B Sun, S Hanai, M Miwa - Biochemical and biophysical …, 2003 - Elsevier
Human T-cell leukemia virus type 1 (HTLV-1) is etiologically linked with HTLV-1-associated
diseases. HTLV-1 proviral load is higher in persons with adult T-cell leukemia and HTLV-1 …