Immunopathogenesis of human T‐cell leukemia virus type‐1‐associated myelopathy/tropical spastic paraparesis: recent perspectives

M Saito, CRM Bangham - Leukemia research and treatment, 2012 - Wiley Online Library
Human T‐cell leukemia virus type‐1 (HTLV‐1) is a replication‐competent human retrovirus
associated with two distinct types of disease only in a minority of infected individuals: the …

Infection of rats with HTLV‐1: a small‐animal model for HTLV‐1 carriers

T Suga, T Kameyama, T Kinoshita… - … journal of cancer, 1991 - Wiley Online Library
A human T‐cell line producing human T‐cell leukemia virus type 1 (HTLV‐1), MT‐2, was
injected intravenously into female F344 rats aged 5 weeks to make HTLV‐1 carrier rats …

Human T-cell leukemia virus type 1: replication, proliferation and propagation by Tax and HTLV-1 bZIP factor

M Matsuoka, J Yasunaga - Current opinion in virology, 2013 - Elsevier
Highlights•HTLV-1 primarily transmits by cell-to-cell contact.•HTLV-1 increases the number
of infected cells by clonal proliferation to facilitate its transmission.•HTLV-1 bZIP factor (HBZ) …

[HTML][HTML] HTLV-1 drives vigorous clonal expansion of infected CD8+ T cells in natural infection

A Melamed, DJ Laydon, H Al Khatib, AG Rowan… - Retrovirology, 2015 - Springer
Abstract Background Human T-lymphotropic Virus Type I (HTLV-1) is a retrovirus that
persistently infects 5–10 million individuals worldwide and causes disabling or fatal …

Human T‐lymphotropic Virus 1 (HTLV‐1) infection–dermatological implications

M Amano, M Setoyama, A Grant… - International Journal of …, 2011 - Wiley Online Library
Human T‐lymphotropic virus type 1 (HTLV‐1) is a type C retrovirus primarily endemic to
Japan, Central and South America, the Middle East, regions of Africa, and the Caribbean …

Peripheral T-lymphocyte activation by human T-cell leukemia virus type I interferes with the CD2 but not with the CD3/TCR pathway

MD Dodon, A Bernard, L Gazzolo - Journal of virology, 1989 - Am Soc Microbiol
Human T-cell leukemia virus type I (HTLV-I) is etiologically associated with adult T-cell
leukemia, an aggressive lymphoproliferative disorder, and with chronic neurological …

[HTML][HTML] Potential role of HTLV-1 Tax-specific cytotoxic t lymphocytes expressing a unique t-cell receptor to promote inflammation of the central nervous system in …

Y Tanaka, T Sato, N Yagishita, J Yamauchi… - Frontiers in …, 2022 - frontiersin.org
Human T-lymphotropic virus 1 (HTLV-1) infection causes two serious diseases: adult T-cell
leukemia/lymphoma (ATL) and HTLV-1-associated myelopathy (HAM). Immunological …

Current approaches for detection of human T‐lymphotropic virus Type 1: A systematic review

M Fani, M Rezayi, Z Meshkat… - Journal of cellular …, 2019 - Wiley Online Library
Background Human T‐lymphotropic virus Type 1 (HTLV‐1) is a retrovirus that is endemic in
some regions of the world. It is known to cause several diseases like adult T‐cell leukemia …

[HTML][HTML] Role of HTLV-1 Tax and HBZ in the pathogenesis of HAM/TSP

Y Enose-Akahata, A Vellucci, S Jacobson - Frontiers in microbiology, 2017 - frontiersin.org
Human T cell lymphotropic virus type 1 (HTLV-1) infection can lead to development of adult
T cell leukemia/lymphoma (ATL) or HTLV-1-associated myelopathy/tropical spastic …

[HTML][HTML] HTLV-1 modulates the frequency and phenotype of FoxP3+CD4+T cells in virus-infected individuals

Y Satou, A Utsunomiya, J Tanabe, M Nakagawa… - Retrovirology, 2012 - Springer
Abstract Background HTLV-1 utilizes CD4 T cells as the main host cell and maintains the
proviral load via clonal proliferation of infected CD4+ T cells. Infection of CD4+ T cells by …