Potentiation of omega-3 fatty acid antidepressant-like effects with low non-antidepressant doses of fluoxetine and mirtazapine

CH Laino, C Fonseca, N Sterin-Speziale… - European Journal of …, 2010 - Elsevier
Despite the advances in psychopharmacology, the treatment of depressive disorders is still
not satisfactory. Side effects and resistance to antidepressant drugs are the greatest …

Fluoxetine potentiation of omega-3 fatty acid antidepressant effect: evaluating pharmacokinetic and brain fatty acid-related aspects in rodents

CH Laino, P Garcia, MF Podestá, C Höcht… - Journal of …, 2014 - Elsevier
We previously reported that combined fluoxetine administration at antidepressant doses
renders additive antidepressant effects, whereas non-antidepressant doses potentiate the …

Augmentation of antidepressants with unsaturated fatty acids omega-3 in drug-resistant depression

K Krawczyk, J Rybakowski - Psychiatria polska, 2012 - europepmc.org
Aim The aim of this paper was to evaluate the impact of augmenting administered
antidepressant treatment of patients suffering from a severe episode of treatment-resistant …

Possible antidepressant mechanisms of omega-3 polyunsaturated fatty acids acting on the central nervous system

L Zhou, JY Xiong, YQ Chai, L Huang, ZY Tang… - Frontiers in …, 2022 - frontiersin.org
Omega-3 polyunsaturated fatty acids (PUFAs) can play important roles in maintaining
mental health and resistance to stress, and omega-3 PUFAs supplementation can display …

Omega-3 fatty acids supplementation in the treatment of depression: An observational study

S Mehdi, K Manohar, A Shariff, N Kinattingal… - Journal of Personalized …, 2023 - mdpi.com
Depression is a common mood disorder characterized by persistent sadness and loss of
interest. Research suggests an association between the inclusion of omega-3 fatty acids in …

Omega-3 fatty acids in major depressive disorder: a preliminary double-blind, placebo-controlled trial

KP Su, SY Huang, CC Chiu, WW Shen - European …, 2003 - Elsevier
Patients with depression have been extensively reported to be associated with the
abnormality of omega-3 polyunsaturated fatty acids (PUFAs), including significantly low …

Effects of omega-3 fatty acid supplementation on mood and emotional information processing in recovered depressed individuals

N Antypa, AHM Smelt, A Strengholt… - Journal of …, 2012 - journals.sagepub.com
Beneficial effects of omega-3 fatty acids have been reported for several psychiatric
disorders, particularly for depression. Association studies show a relationship between …

Are omega-3 fatty acids antidepressants or just mood-improving agents? The effect depends upon diagnosis, supplement preparation, and severity of depression

PY Lin, D Mischoulon, MP Freeman, Y Matsuoka… - Molecular …, 2012 - nature.com
The use of omega-3 fatty acids for depression treatment is of considerable interest, in part
due to the inadequate efficacy and tolerability of standard antidepressant medications …

[PDF][PDF] Neurobehavioral aspects of omega-3 fatty acids: possible mechanisms and therapeutic value in major depression

AC Logan - Alternative medicine review, 2003 - anaturalhealingcenter.com
Omega-3 fatty acids have been the subject of volumes of international research, the results
of which indicate these substances may have therapeutic value in a number of medical …

What is the effectiveness of the use of polyunsaturated fatty acid omega-3 in the treatment of depression?

DM Rocha Araujo, MM Vilarim… - Expert review of …, 2010 - Taylor & Francis
This systematic review aims to identify the effect of polyunsaturated fatty acid omega-3 on
depressive disorder. A bibliographical search was conducted in the databases SciELO …