[HTML][HTML] Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies
LM Gittings, R Sattler - Faculty reviews, 2020 - ncbi.nlm.nih.gov
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that is
characterized by degeneration of both upper and lower motor neurons and subsequent …
characterized by degeneration of both upper and lower motor neurons and subsequent …
Therapeutic development in amyotrophic lateral sclerosis
M Bucchia, A Ramirez, V Parente, C Simone… - Clinical …, 2015 - Elsevier
Purpose Amyotrophic lateral sclerosis (ALS) is the most common motor neuron disease in
adults. It is almost invariably lethal within a few years after the onset of symptoms. No …
adults. It is almost invariably lethal within a few years after the onset of symptoms. No …
Amyotrophic lateral sclerosis: update and new developments
Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease. It is
typically characterized by adult-onset degeneration of the upper and lower motor neurons …
typically characterized by adult-onset degeneration of the upper and lower motor neurons …
Understanding ALS: new therapeutic approaches
A Musarò - The FEBS journal, 2013 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease associated with
motor neuron degeneration, muscle atrophy and paralysis. Although numerous pathological …
motor neuron degeneration, muscle atrophy and paralysis. Although numerous pathological …
Roots to start research in amyotrophic lateral sclerosis: molecular pathways and novel therapeutics for future
D Harikrishnareddy, S Misra, S Upadhyay… - Reviews in the …, 2015 - degruyter.com
Amyotrophic lateral sclerosis (ALS) is a devastating neurological disease that rapidly
progresses from mild motor symptoms to severe motor paralysis and premature death. There …
progresses from mild motor symptoms to severe motor paralysis and premature death. There …
[HTML][HTML] Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation
Amyotrophic lateral sclerosis (ALS) is a devastating disease caused by degeneration of
motor neurons. As with all major neurodegenerative disorders, development of disease …
motor neurons. As with all major neurodegenerative disorders, development of disease …
[HTML][HTML] Clinical manifestation and management of amyotrophic lateral sclerosis
A Verma - 2021 - europepmc.org
Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodegenerative disease
resulting in death in 2 to 4 years in most cases. There are several clinical subtypes of ALS …
resulting in death in 2 to 4 years in most cases. There are several clinical subtypes of ALS …
[HTML][HTML] Challenges in the understanding and treatment of amyotrophic lateral sclerosis/motor neuron disease
J Rosenfeld, MJ Strong - Neurotherapeutics, 2015 - Elsevier
With the acceleration in our understanding of ALS and the related motor neuron disease has
come even greater challenges in reconciling all of the proposed pathogenic mechanisms …
come even greater challenges in reconciling all of the proposed pathogenic mechanisms …
[HTML][HTML] Recent advances in amyotrophic lateral sclerosis
ALS is a relentlessly progressive and fatal disease, with no curative therapies available to
date. Symptomatic and palliative care, provided in a multidisciplinary context, still remains …
date. Symptomatic and palliative care, provided in a multidisciplinary context, still remains …
[PDF][PDF] ALS genetics: gains, losses, and implications for future therapies
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder caused by the loss
of motor neurons from the brain and spinal cord. The ALS community has made remarkable …
of motor neurons from the brain and spinal cord. The ALS community has made remarkable …