Effect of vascular radioactivity on regional values of cerebral blood flow: evaluation of methods for H215O PET to distinguish cerebral perfusion from blood volume

H Okazawa, M Vafaee - Journal of Nuclear Medicine, 2001 - Soc Nuclear Med
To evaluate the appropriate model for calculating regional cerebral blood flow (rCBF) with
PET and H215O, the values obtained from 1-and 2-compartment analyses were compared …

Proposal of blood volume-corrected model for quantification of regional cerebral blood flow with H2 15O-PET and its application to AVF

C Seki, T Momose, Y Kojima, Y Sasaki, K Ohtomo… - Radiation …, 2006 - Springer
Purpose It is generally assumed that vascular tracer activity is negligible in the quantification
of regional cerebral blood flow (rCBF) with H 2 15 O and positron emission tomography …

Quantitative cerebral H2 15O perfusion PET without arterial blood sampling, a method based on washout rate

V Treyer, M Jobin, C Burger, V Teneggi… - European journal of …, 2003 - Springer
The quantitative determination of regional cerebral blood flow (rCBF) is important in certain
clinical and research applications. The disadvantage of most quantitative methods using H 2 …

Noninvasive method for measurement of cerebral blood flow using O-15 water PET/MRI with ASL correlation

H Okazawa, Y Higashino, T Tsujikawa… - European Journal of …, 2018 - Elsevier
Purpose A noninvasive image derived input function (IDIF) method was applied to estimate
arterial input function from brain H 2 15 O-PET/MRI images for the measurement of cerebral …

Cerebral blood flow with the continuous infusion of oxygen-15-labeled water

SC Jones, JH Greenberg, R Dann… - Journal of Cerebral …, 1985 - journals.sagepub.com
This work describes the determination of CBF in eight normal human subjects with positron
emission tomographic (PET) imaging using the continuous intravenous infusion of H215O. A …

Quantitation of regional cerebral blood flow corrected for partial volume effect using O-15 water and PET: II. Normal values and gray matter blood flow response to …

I Law, H Iida, S Holm, S Nour… - Journal of Cerebral …, 2000 - journals.sagepub.com
One of the most limiting factors for the accurate quantification of physiologic parameters with
positron emission tomography (PET) is the partial volume effect (PVE). To assess the …

A System for Cerebral Blood Flow Measurement Using an H215O Autoradiographic Method and Positron Emission Tomography

I Kanno, H Iida, S Miura, M Murakami… - Journal of Cerebral …, 1987 - journals.sagepub.com
A system for CBF measurement using an H215O autoradiographic method and positron
emission tomography (PET) has been designed and installed as a clinical tool. Following an …

Arterial fraction of cerebral blood volume in humans measured by positron emission tomography

H Ito, I Kanno, H Iida, J Hatazawa… - Annals of nuclear …, 2001 - Springer
In quantitative functional neuroimaging with positron emission tomography (PET) and
magnetic resonance imaging (MRI), cerebral blood volume (CBV) and its three components …

Quantitation of regional cerebral blood flow corrected for partial volume effect using O-15 water and PET: I. Theory, error analysis, and stereologic comparison

H Iida, I Law, B Pakkenberg… - Journal of Cerebral …, 2000 - journals.sagepub.com
Limited spatial resolution of positron emission tomography (PET) can cause significant
underestimation in the observed regional radioactivity concentration (so-called partial …

Pitfalls of regional cerebral blood flow analysis in cerebrovascular disease

HL LAGREZE, RL LEVINE… - Clinical nuclear …, 1988 - journals.lww.com
In 20 patients with unilateral cerebrovascular disease, regional cerebral blood flow (rCBF)
was measured by F-18-fluoromethane inhalation and positron emission tomography (PET) …