Fat taste signal transduction and its possible negative modulator components

D Shanmugamprema, K Muthuswamy… - Progress in Lipid …, 2020 - Elsevier
The incidence of obesity and its associated diseases including diabetes and various
cardiovascular disease continues to escalate. Since the energy homeostasis executes a …

A systematic review of the biological mediators of fat taste and smell

RB Jaime-Lara, BE Brooks, C Vizioli… - Physiological …, 2023 - journals.physiology.org
Taste and smell play a key role in our ability to perceive foods. Overconsumption of highly
palatable energy-dense foods can lead to increased caloric intake and obesity. Thus there is …

Preference for dietary fat: From detection to disease

AS Khan, R Keast, NA Khan - Progress in lipid research, 2020 - Elsevier
Recent advances in the field of taste physiology have clarified the role of different basic taste
modalities and their implications in health and disease and proposed emphatically that there …

Cell signaling mechanisms of gustatory perception of lipids: can the taste cells be the target of anti-obesity agents?

G Dramane, S Akpona, AM Simonin… - Current medicinal …, 2011 - ingentaconnect.com
It has been well propounded that there exists five basic taste modalities, eg, sweet, sour,
bitter, salty and umami. Recent compelling evidence from rodents and human beings raises …

Cellular and molecular mechanisms of fat taste perception

A Hichami, AS Khan, NA Khan - The Pharmacology of Taste, 2021 - Springer
During the last couples of years, a number of studies have increasingly accumulated on the
gustatory perception of dietary fatty acids in rodent models and human beings in health and …

Taste of fat: a sixth taste modality?

P Besnard, P Passilly-Degrace… - Physiological …, 2016 - journals.physiology.org
An attraction for palatable foods rich in lipids is shared by rodents and humans. Over the last
decade, the mechanisms responsible for this specific eating behavior have been actively …

Novel fat taste receptor agonists curtail progressive weight gain in obese male mice

AS Khan, A Hichami, B Murtaza… - Cellular and Molecular …, 2023 - Elsevier
Background & Aims The spontaneous preference for dietary lipids is principally regulated by
2 lingual fat taste receptors, CD36 and GPR120. Obese animals and most of human …

[HTML][HTML] Mechanism of fat taste perception: Association with diet and obesity

D Liu, N Archer, K Duesing, G Hannan, R Keast - Progress in lipid research, 2016 - Elsevier
Energy homeostasis plays a significant role in food consumption and body weight regulation
with fat intake being an area of particular interest due to its palatability and high energy …

Insights on modulators in perception of taste modalities: a review

S Deepankumar, M Karthi, K Vasanth… - Nutrition research …, 2019 - cambridge.org
A major challenge in taste research is to overcome the flavour imperfections in food products
and to build nutritious strategies to combat against obesity as well as other related metabolic …

Evidence for presence of nonesterified fatty acids as potential gustatory signaling molecules in humans

B Kulkarni, R Mattes - Chemical senses, 2013 - academic.oup.com
Gustatory fatty acid signaling termed “fatty acid taste” is initiated when nonesterified fatty
acids (NEFA) bind to putative fat receptors on taste receptor cells. However, the source and …