Molecular regulation of brain metabolism underlying circadian epilepsy
Extensive study has demonstrated that epilepsy occurs with greater frequency at certain
times in the 24‐h cycle. Although these findings implicate an overlap between the circadian …
times in the 24‐h cycle. Although these findings implicate an overlap between the circadian …
[HTML][HTML] Decoding circadian rhythm and epileptic activities: clues from animal studies
The relationship between circadian rhythm and epilepsy has been recognized for decades.
Yet many questions underlying the complex mechanisms of their interaction remain elusive …
Yet many questions underlying the complex mechanisms of their interaction remain elusive …
[HTML][HTML] The molecular genetic interaction between circadian rhythms and susceptibility to seizures and epilepsy
CJ Re, AI Batterman, JR Gerstner, RJ Buono… - Frontiers in …, 2020 - frontiersin.org
Seizure patterns observed in patients with epilepsy suggest that circadian rhythms and
sleep/wake mechanisms play some role in the disease. This review addresses key topics in …
sleep/wake mechanisms play some role in the disease. This review addresses key topics in …
[HTML][HTML] Molecular mechanism of circadian rhythmicity of seizures in temporal lobe epilepsy
CH Cho - Frontiers in cellular neuroscience, 2012 - frontiersin.org
The circadian pattern of seizures in people with epilepsy was first described two millennia
ago. However, these phenomena have not received enough scientific attention, possibly …
ago. However, these phenomena have not received enough scientific attention, possibly …
Diurnal circadian clock gene expression is altered in models of genetic and acquired epilepsy
Objectives Growing evidence demonstrates a relationship between epilepsy and the
circadian system. However, relatively little is known about circadian function in disease …
circadian system. However, relatively little is known about circadian function in disease …
The circadian dynamics of the hippocampal transcriptome and proteome is altered in experimental temporal lobe epilepsy
KJ Debski, N Ceglia, A Ghestem, AI Ivanov… - Science …, 2020 - science.org
Gene and protein expressions display circadian oscillations, which can be disrupted in
diseases in most body organs. Whether these oscillations occur in the healthy hippocampus …
diseases in most body organs. Whether these oscillations occur in the healthy hippocampus …
Circadian/multidien molecular oscillations and rhythmicity of epilepsy (MORE)
C Bernard - Epilepsia, 2021 - Wiley Online Library
The occurrence of seizures at specific times of the day has been consistently observed for
centuries in individuals with epilepsy. Electrophysiological recordings provide evidence that …
centuries in individuals with epilepsy. Electrophysiological recordings provide evidence that …
[HTML][HTML] Epilepsy and its interaction with sleep and circadian rhythm
B Jin, T Aung, Y Geng, S Wang - Frontiers in Neurology, 2020 - frontiersin.org
Growing evidence shows the bidirectional interactions between sleep, circadian rhythm, and
epilepsy. Comprehending how these interact with each other may help to advance our …
epilepsy. Comprehending how these interact with each other may help to advance our …
Seizure pathways change on circadian and slower timescales in individual patients with focal epilepsy
GM Schroeder, B Diehl… - Proceedings of the …, 2020 - National Acad Sciences
Personalized medicine requires that treatments adapt to not only the patient but also
changing factors within each individual. Although epilepsy is a dynamic disorder …
changing factors within each individual. Although epilepsy is a dynamic disorder …
Circadian rhythms: interactions with seizures and epilepsy
M Quigg - Epilepsy research, 2000 - Elsevier
Circadian rhythms are endogenously-mediated 24 h cycles of behavioral or physiological
activity. The interactions among the mammalian circadian clock, acute seizures, and chronic …
activity. The interactions among the mammalian circadian clock, acute seizures, and chronic …