Transmission Efficiency of Plasmodium falciparum Malaria Resistant Strains in the African Mosquito Vectors

EM Sarah-Matio - 2021 - theses.hal.science
Malaria remains a public health problem in Cameroon and antimalarial drug resistance
hampers proper control of the disease. Several studies have been carried out on …

The Rare, the Best: Spread of Antimalarial-Resistant Plasmodium falciparum Parasites by Anopheles Mosquito Vectors

A Berry, S Menard, SE Nsango, L Abate… - Microbiology …, 2021 - Am Soc Microbiol
The emergence of resistance to antimalarials has prompted the steady switch to novel
therapies for decades. Withdrawal of antimalarials, such as chloroquine in sub-Saharan …

Population biology and antimalarial resistance: The transmission of antimalarial drug resistance in Plasmodium falciparum

KI Barnes, NJ White - Acta tropica, 2005 - Elsevier
Malaria morbidity and mortality continue to increase across sub-Saharan Africa. This is
largely as a result of the continued use of chloroquine and sulfadoxine-pyrimethamine …

Putative molecular markers of Plasmodium falciparum resistance to antimalarial drugs in malaria parasites from Ghana

SA Matrevi, T Adams, KZ Tandoh… - Frontiers in …, 2024 - frontiersin.org
Introduction Antimalarial drugs including artemisinin-based combination therapy (ACT)
regimens and sulphadoxine-pyrimethamine (SP) are used in Ghana for malaria therapeutics …

[HTML][HTML] Mosquitoes as a feasible sentinel group for anti-malarial resistance surveillance by Next Generation Sequencing of Plasmodium falciparum

R Smith-Aguasca, H Gupta, E Uberegui, M Maquina… - Malaria journal, 2019 - Springer
Background Plasmodium falciparum drug resistance surveillance is key to successful
disease control and eradication. Contemporary methods that only allow determination of …

[HTML][HTML] Selection for chloroquine-sensitive Plasmodium falciparum by wild Anopheles arabiensis in Southern Zambia

S Mharakurwa, M Sialumano, K Liu, A Scott, P Thuma - Malaria journal, 2013 - Springer
Background The emergence of parasite drug resistance, especially Plasmodium falciparum,
persists as a major obstacle for malaria control and elimination. To develop effective public …

[HTML][HTML] The landscape of drug resistance in Plasmodium falciparum malaria in the Democratic Republic of Congo: a mapping systematic review

NK Kayiba, E Tshibangu-Kabamba… - Tropical Medicine and …, 2023 - Springer
Abstract Context The Democratic Republic of Congo (DRC), one of the most malaria-
affected countries worldwide, is a potential hub for global drug-resistant malaria. This study …

[HTML][HTML] Status of the Multidrug Resistance-1 Gene of Plasmodium falciparum in Four Malaria Epidemiological Strata, Two Decades after the Abolition of Chloroquine …

DD Sofeu-Feugaing, FN Ajonglefac… - Journal of Tropical …, 2023 - ncbi.nlm.nih.gov
Drug-resistant malaria parasites pose a threat to global malaria control efforts, and it is
important to know the extent of these drug-resistant mutations in each region to determine …

Geographical emergence of sulfadoxine-pyrimethamine drug resistance-associated P. falciparum and P. malariae alleles in co-existing Anopheles mosquito and …

FN Nkemngo, LW Raissa, DN Nguete… - Antimicrobial agents …, 2023 - Am Soc Microbiol
Malaria molecular surveillance remains critical in detecting and tracking emerging parasite
resistance to anti-malarial drugs. The current study employed molecular techniques to …

Plasmodium falciparum genetic diversity in coincident human and mosquito hosts

Z Lapp, AA Obala, L Abel, DA Rasmussen, KM Sumner… - Mbio, 2022 - Am Soc Microbiol
Population genetic diversity of Plasmodium falciparum antigenic loci is high despite large
bottlenecks in population size during the parasite life cycle. The prevalence of genetically …