Digital twin reveals combinatorial code of non-linear computations in the mouse primary visual cortex

I Ustyuzhaninov, MF Burg, SA Cadena, J Fu… - bioRxiv, 2022 - biorxiv.org
More than a dozen excitatory cell types have been identified in the mouse primary visual
cortex (V1) based on transcriptomic, morphological and in vitro electrophysiological …

[HTML][HTML] Connecting single-cell transcriptomes to projectomes in mouse visual cortex

SA Sorensen, NW Gouwens, Y Wang, M Mallory… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The mammalian brain is composed of diverse neuron types that play different functional
roles. Recent single-cell RNA sequencing approaches have led to a whole brain taxonomy …

Functional triplet motifs underlie accurate predictions of single-trial responses in populations of tuned and untuned V1 neurons

JB Dechery, JN MacLean - PLoS computational biology, 2018 - journals.plos.org
Visual stimuli evoke activity in visual cortical neuronal populations. Neuronal activity can be
selectively modulated by particular visual stimulus parameters, such as the direction of a …

The Sensorium competition on predicting large-scale mouse primary visual cortex activity

KF Willeke, PG Fahey, M Bashiri, L Pede… - arXiv preprint arXiv …, 2022 - arxiv.org
The neural underpinning of the biological visual system is challenging to study
experimentally, in particular as the neuronal activity becomes increasingly nonlinear with …

Deep learning-driven characterization of single cell tuning in primate visual area V4 unveils topological organization

KF Willeke, K Restivo, K Franke, AF Nix, SA Cadena… - bioRxiv, 2023 - biorxiv.org
Deciphering the brain's structure-function relationship is key to understanding the neuronal
mechanisms underlying perception and cognition. The cortical column, a vertical …

Functional connectomics spanning multiple areas of mouse visual cortex

MICrONS Consortium, JA Bae, M Baptiste, CA Bishop… - BioRxiv, 2021 - biorxiv.org
To understand the brain we must relate neurons' functional responses to the circuit
architecture that shapes them. Here, we present a large functional connectomics dataset …

Modeling robust and efficient coding in the mouse primary visual cortex using computational perturbations

B Cai, YN Billeh, SN Chettih, CD Harvey, C Koch… - bioRxiv, 2020 - biorxiv.org
Investigating how visual inputs are encoded in visual cortex is important for elucidating the
roles of cell populations in circuit computations. We here use a recently developed, large …

[PDF][PDF] Segregated encoding of spatiotemporal features in the mouse visual cortex

X Han, B Vermaercke, V Bonin - bioRxiv, 2018 - scholar.archive.org
Understanding visual processing requires a detailed description of computations performed
by 12 neurons across stages of the visual system. However, the diverse tunings of neurons …

High-accuracy decoding of complex visual scenes from neuronal calcium responses

RJ Ellis, M Michaelides - BioRxiv, 2018 - biorxiv.org
The brain contains billions of neurons defined by diverse cytoarchitectural, anatomical,
genetic, and functional properties. Sensory encoding and decoding are popular research …

Associations between in vitro, in vivo and in silico cell classes in mouse primary visual cortex

Y Wei, A Nandi, X Jia, JH Siegle, D Denman… - Nature …, 2023 - nature.com
The brain consists of many cell classes yet in vivo electrophysiology recordings are typically
unable to identify and monitor their activity in the behaving animal. Here, we employed a …