Is there a pharmacodynamic need for the use of continuous versus intermittent infusion with ceftazidime against Pseudomonas aeruginosa? An in vitro …
L Alou, L Aguilar, D Sevillano… - Journal of …, 2005 - academic.oup.com
Objectives: In order to explore the pharmacodynamic need for continuous versus intermittent
(three times a day) administration of ceftazidime in critically ill patients, a pharmacokinetic …
(three times a day) administration of ceftazidime in critically ill patients, a pharmacokinetic …
Killing of Pseudomonas aeruginosa during continuous and intermittent infusion of ceftazidime in an in vitro pharmacokinetic model
JW Mouton, JG Den Hollander - Antimicrobial agents and …, 1994 - Am Soc Microbiol
An in vitro pharmacokinetic model mimicking human serum drug concentrations, based on a
dialyzer unit, was developed to study the efficacies of continuous infusion and intermittent …
dialyzer unit, was developed to study the efficacies of continuous infusion and intermittent …
Continuous infusion versus intermittent administration of ceftazidime in critically ill patients with suspected gram-negative infections
AS Benko, DM Cappelletty, JA Kruse… - Antimicrobial agents …, 1996 - Am Soc Microbiol
The pharmacodynamics and pharmacokinetics of ceftazidime administered by continuous
infusion and intermittent bolus over a 4-day period were compared. We conducted a …
infusion and intermittent bolus over a 4-day period were compared. We conducted a …
Serum bactericidal activity of ceftazidime: continuous infusion versus intermittent injections
DP Nicolau, CH Nightingale… - Antimicrobial agents …, 1996 - Am Soc Microbiol
Since beta-lactam antibiotics have concentration-independent killing, bacterial eradication is
a function of the time the serum drug concentration remains above the drug's MIC (T> MIC) …
a function of the time the serum drug concentration remains above the drug's MIC (T> MIC) …
Pharmacodynamics of ceftazidime administered as continuous infusion or intermittent bolus alone and in combination with single daily-dose amikacin against …
DM Cappelletty, SL Kang, SM Palmer… - Antimicrobial agents …, 1995 - Am Soc Microbiol
We compared the pharmacodynamics and killing activity of ceftazidime, administered by
continuous infusion and intermittent bolus, against Pseudomonas aeruginosa ATCC 27853 …
continuous infusion and intermittent bolus, against Pseudomonas aeruginosa ATCC 27853 …
Intermittent bolus dosing of ceftazidime in critically ill patients.
RJ Young, J Lipman, T Gin… - The Journal of …, 1997 - academic.oup.com
Ceftazidime is frequently used in critically ill patients, particularly for the treatment of
Pseudomonas aeruginosa infections. The recommended dosing regimen is based on …
Pseudomonas aeruginosa infections. The recommended dosing regimen is based on …
[HTML][HTML] Population pharmacokinetics and probability of target attainment of different dosing regimens of ceftazidime in critically ill patients with a proven or suspected …
A Werumeus Buning, CJ Hodiamont, NM Lechner… - Antibiotics, 2021 - mdpi.com
Altered pharmacokinetics (PK) of hydrophilic antibiotics in critically ill patients is common,
with possible consequences for efficacy and resistance. We aimed to describe ceftazidime …
with possible consequences for efficacy and resistance. We aimed to describe ceftazidime …
Comparative In Vitro and In Vivo Efficacies of Human Simulated Doses of Ceftazidime and Ceftazidime-Avibactam against Pseudomonas aeruginosa
JL Crandon, VJ Schuck, MA Banevicius… - Antimicrobial agents …, 2012 - Am Soc Microbiol
The combination of ceftazidime and avibactam possesses potent activity against resistant
Gram-negative pathogens, including Pseudomonas aeruginosa. We compared the …
Gram-negative pathogens, including Pseudomonas aeruginosa. We compared the …
Pharmacokinetics and pharmacodynamics of continuous and intermittent ceftazidime during the treatment of nosocomial pneumonia
DP Nicolau, JC McNabb, MK Lacy, J Li… - Clinical drug …, 1999 - Springer
Objective: This study aimed too compare the pharmacokinetic and pharmacodynamic profile
of intermittent and continuously infused ceftazidime in patients with nosocomial pneumonia …
of intermittent and continuously infused ceftazidime in patients with nosocomial pneumonia …
Pharmacodynamics of Intermittent- and Continuous-Infusion Cefepime Alone and in Combination with Once-Daily Tobramycin against Pseudomonas aeruginosa in …
PR Tessier, DP Nicolau, CO Onyeji, CH Nightingale - Chemotherapy, 1999 - karger.com
Cefepime, a fourth-generation cephalosporin, is currently one of the primary agents used in
combination with an aminoglycoside when treating Pseudomonas aeruginosa infections …
combination with an aminoglycoside when treating Pseudomonas aeruginosa infections …
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