Background Highly sensitive and specific urinary biomarkers for the early detection of
bladder cancer (BC) to improve the performance of urinary cytology are needed. Objective …

Background Current standard methods used to detect and monitor bladder cancer (BC) are
invasive or have low sensitivity. This study aimed to develop a urine methylation biomarker …

BACKGROUND Current methods for the detection and surveillance of bladder cancer (BCa)
are often invasive and/or possess suboptimal sensitivity and specificity, especially in early …

Background The development of accurate urinary biomarkers for non-invasive and cost-
effective detection of primary and recurrent bladder tumours is recognized as one of the …

Background Current non-invasive tests have limited sensitivities and lack capabilities of pre-
operative risk stratification for bladder cancer (BC) diagnosis. We aimed to develop and …

Background Better prognostic outcome is closely correlated with early detection of bladder
cancer. Current non-invasive urianalysis relies on simultaneously testing multiple …

Aim: To analyze the potential of 14 cancer-associated genes, including six miRNAs, for
bladder cancer (BC) diagnosis in urine. Patients & methods: DNA methylation levels of 14 …

Background Aberrant DNA methylation status early in carcinogenesis represents a potential
indicator of tumor detection. We would like to establish a DNA methylation biomarker panel …

Genitourinary (prostate, bladder, and kidney) cancers together comprise the most common
type of human neoplasms. As a common feature to these types of malignancy, the disease is …

Purpose Changes in DNA methylation of tumor suppressor genes early in carcinogenesis
represent potential indicators of cancer detection and disease evolution. We examined the …