Today, it is very challenging to develop new active pharmaceutical ingredients. Developing
good preparations of well-recognized natural medicines is certainly a practical and …

Drug metabolism plays vital roles in the absorption and pharmacological activity of poorly
soluble natural medicines. It is important to choose suitable delivery systems to increase the …

Drug metabolism plays an important role in the drug disposal process. Differences in
pharmacokinetics among individuals are the basis for personalized medicine. Natural …

Lipid based drug delivery system such as Solid lipid nanoparticle (SLN) and Nanostructured
lipid carriers (NLC) are among the most promising drug delivery system used in many …

Oral administration remains the most preferred route for the treatment of many diseases due
to its convenience and adaptability. However, the presystemic metabolism may be an …

Nowadays exploration of novel lipid-based formulations is akin to a magnet for researchers
worldwide for improving the in vivo performance of highly lipophilic drugs. Over the last few …

Drug delivery via the oral route has always been challenging for poorly soluble drugs. Acid‐
induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the …

The development of natural products for potential new drugs faces obstacles such as
unknown mechanisms, poor solubility, and limited bioavailability, which limit the broadened …

Enteral administration is the most convenient route despite the gastrointestinal physiological
barriers. Nanostructured lipid carriers (NLCs) have emerged as a promising strategy for …

Poor solubility remains a major challenge for pharmaceutical industry, which is now
considered to be an area of prime importance in the field of biomedical research …