Heart failure secondary to myocardial infarction (MI) remains a major source of morbidity
and mortality. Long-term outcome after MI can be largely be defined in terms of its impact on …

Over the last 50 years, studies investigating the pathogenesis of left ventricular dysfunction
have resulted in many potential therapeutic targets being identified and novel classes of …

While mortality from overt ischaemic heart disease is falling, that from heart failure is
increasing and reaching epidemic proportions. 1 Although an aging population is partly …

Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

This review briefly highlights the major mechanisms of left ventricular (LV) remodeling
following myocardial infarction in heart failure and presents novel strategies to limit infarct …

Most patients survive acute myocardial infarction (MI). Yet this encouraging development
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …

Left ventricular (LV) remodelling remains an important treatment target in patients after
myocardial infarction (MI) and chronic heart failure (CHF). Accumulating evidence has …

As more patients survive myocardial infarctions, the incidence of heart failure increases.
After an infarction, the human heart undergoes a series of structural changes, which are …

Early reperfusion of totally occluded coronary arteries with thrombolysis and/or
percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) reduces …

Background: A major advance in understanding the pathophysiology of the heart failure
syndrome has been an understanding of the process of left ventricular (LV) remodeling. After …