Testosterone: an overview of biosynthesis, transport, metabolism and nongenomic actions

FFG Rommerts - Testosterone: Action-Deficiency-Substitution, 1998 - Springer
In the male androgens are essential for the development and maintenance of specific
reproductive tissues such as testis, prostate, epididymis, seminal vesicle and penis, as well …

Role of androgens in the ovary

KA Walters, DJ Handelsman - Molecular and cellular endocrinology, 2018 - Elsevier
It has been well established for decades that androgens, namely testosterone (T) plays an
important role in female reproductive physiology as the precursor for oestradiol (E 2) …

Androgen physiology

SL Davison, R Bell - Seminars in reproductive medicine, 2006 - thieme-connect.com
Androgen receptors are present in numerous tissues throughout the female body, and
knowledge of the specific actions of androgens at different sites is increasing, along with the …

Molecular mechanisms of androgen action–a historical perspective

AO Brinkmann - Androgen Action: Methods and Protocols, 2011 - Springer
Androgens and the androgen receptor (AR) are indispensable for expression of the male
phenotype. The two most important androgens are testosterone and 5α-dihydrotestosterone …

[HTML][HTML] Intracrine androgen biosynthesis, metabolism and action revisited

L Schiffer, W Arlt, KH Storbeck - Molecular and cellular endocrinology, 2018 - Elsevier
Androgens play an important role in metabolic homeostasis and reproductive health in both
men and women. Androgen signalling is dependent on androgen receptor activation, mostly …

Recent advances in androgen receptor action

HJ Lee, C Chang - Cellular and Molecular Life Sciences CMLS, 2003 - Springer
Androgens, principally testosterone and 5α-dihydrotestosterone, play critical roles in the
development and growth of the male reproductive and nonreproductive systems. Their …

Molecular mechanism of androgen action

RA Hiipakka, S Liao - Trends in Endocrinology & Metabolism, 1998 - cell.com
Androgens affect the growth and development of a wide variety of cell types in both males
and females and produce their effects by binding to androgen receptors, which modulate the …

Steroid biosynthesis and prostate cancer

N Sharifi, RJ Auchus - Steroids, 2012 - Elsevier
The pathways of androgen biosynthesis in human beings have been studied for decades,
and the major pathways and enzymes responsible for testosterone and dihydrotestosterone …

[HTML][HTML] Impact of estrogens in males and androgens in females

SR Hammes, ER Levin - The Journal of clinical …, 2019 - Am Soc Clin Investig
Androgens and estrogens are known to be critical regulators of mammalian physiology and
development. While these two classes of steroids share similar structures (in general …

Androgens during infancy, childhood, and adolescence: physiology and use in clinical practice

KA Mason, MJ Schoelwer, AD Rogol - Endocrine Reviews, 2020 - academic.oup.com
We provide an in-depth review of the role of androgens in male maturation and
development, from the fetal stage through adolescence into emerging adulthood, and …