Adolescent idiopathic scoliosis: a review of aetiological theories of a multifactorial disease

S Marya, AD Tambe, PA Millner… - The Bone & Joint …, 2022 - boneandjoint.org.uk
Adolescent idiopathic scoliosis (AIS), defined by an age at presentation of 11 to 18 years,
has a prevalence of 0.47% and accounts for approximately 90% of all cases of idiopathic …

Recent advances in the aetiology of adolescent idiopathic scoliosis

KMC Cheung, T Wang, GX Qiu, KDK Luk - International orthopaedics, 2008 - Springer
The aetiology of adolescent idiopathic scoliosis (AIS) is still unknown despite many years of
research effort. Theories on AIS's aetiology have included mechanical, hormonal, metabolic …

Idiopathic scoliosis: etiological concepts and hypotheses

R Dayer, T Haumont, W Belaieff… - Journal of children's …, 2013 - journals.sagepub.com
Scoliosis is diagnosed as idiopathic in 70% of structural deformities affecting the spine in
children and adolescents, probably reflecting our current misunderstanding of this disease …

Whither the etiopathogenesis (and scoliogeny) of adolescent idiopathic scoliosis

RG Burwell, PH Dangerfield - Stud Health Technol Inform, 2012 - books.google.com
Although considerable progress had been made in the past two decades in understanding
the etiopathogenesis of adolescent idiopathic scoliosis (AIS), it still lacks an agreed theory of …

[HTML][HTML] Suppl-9, M3: Etiological Theories of Adolescent Idiopathic Scoliosis: Past and Present

M Fadzan, J Bettany-Saltikov - The open orthopaedics journal, 2017 - ncbi.nlm.nih.gov
Adolescent idiopathic scoliosis is one of the most common spinal deformities, yet its cause is
unknown. Various theories look to biomechanical, neuromuscular, genetic, and …

[HTML][HTML] A decade in review after idiopathic scoliosis was first called a Complex trait—a tribute to the late Dr. Yves Cotrel for his support in studies of etiology of …

NLS Tang, MB Dobbs, CA Gurnett, Y Qiu, TP Lam… - Genes, 2021 - mdpi.com
Adolescent Idiopathic Scoliosis (AIS) is a prevalent and important spine disorder in the
pediatric age group. An increased family tendency was observed for a long time, but the …

Idiopathic scoliosis: cracking the genetic code and what does it mean?

NH Miller - Journal of Pediatric Orthopaedics, 2011 - journals.lww.com
Idiopathic scoliosis is one of the most common complex genetic disorders of the
musculoskeletal system. The clinical parameters relating to onset, curve progression, and …

[HTML][HTML] Genetics and pathogenesis of idiopathic scoliosis

A Grauers, E Einarsdottir, P Gerdhem - Scoliosis and spinal disorders, 2016 - Springer
Idiopathic scoliosis (IS), the most common spinal deformity, affects otherwise healthy
children and adolescents during growth. The aetiology is still unknown, although genetic …

From genetics to epigenetics to unravel the etiology of adolescent idiopathic scoliosis

G Pérez-Machado, E Berenguer-Pascual… - Bone, 2020 - Elsevier
Scoliosis is defined as the three-dimensional (3D) structural deformity of the spine with a
radiological lateral Cobb angle (a measure of spinal curvature) of≥ 10° that can be caused …

Top theories for the etiopathogenesis of adolescent idiopathic scoliosis

WJ Wang, HY Yeung, WCW Chu… - Journal of Pediatric …, 2011 - journals.lww.com
Background Despite considerable advances in the past few decades, there is no generally
accepted “top theory or theories” of the etiology of adolescent idiopathic scoliosis (AIS). This …