Propose Understanding the protective effect of exercise against ethanol-induced toxicity
through the oxidative stress signaling pathway, apoptosis, and cholesterol metabolism is …

Chronic excessive drinking leads to myocardial contractile dysfunction and dilated
cardiomyopathy, where ethanol toxicity plays an essential role. Cytochrome P450 (CYP) …

Alcoholic liver disease (ALD) has caused a serious burden on public and personal health in
crowd with ethanol abuse. The effects of insulin resistance (IR) on ALD and the mechanisms …

Objectives Binge drinking and alcohol toxicity are often associated with myocardial
dysfunction possibly due to accumulation of the ethanol metabolite acetaldehyde although …

The association between ethanol consumption and heart abnormalities, such as chamber
dilation, myocyte damage, ventricular hypertrophy, and hypertension is well known …

Alcoholic liver disease (ALD) has become an important liver disease hazard to public and
personal health. Oxidative stress is believed to be responsible for the pathological changes …

Binge drinking of alcohol is known to cause cardiac dysfunction in some drinkers. This study
was designed to examine the effect of ethanol on rat heart tissue with an experimental …

Binge drinking of alcohol causes cardiac dysfunction in some people. The mechanism
remains unclear. This study was designed to investigate high doses of alcohol-induced …

Abstract Tert-butylhydroquinone (tBHQ), an inducer of nuclear factor erythroid 2-related
factor 2 (Nrf2), has been demonstrated to attenuate oxidative stress-induced injury and the …

CYP2E1 metabolizes ethanol leading to production of reactive oxygen species (ROS) and
acetaldehyde, which are known to cause not only liver damage but also toxicity to other …