No-reflow: a heterogeneous clinical phenomenon with multiple therapeutic strategies

L Galiuto, F Crea - Current pharmaceutical design, 2006 - ingentaconnect.com
Previously defined as a shotcoming to achieve uniform intramyocardial reperfusion after
prolonged but reversible coronary occlusion, only recently has no-reflow phenomenon been …

Management of the no-reflow phenomenon

MJ Butler, W Chan, AJ Taylor, AM Dart… - Pharmacology & …, 2011 - Elsevier
The lack of reperfusion of myocardium after prolonged ischaemia that may occur despite
opening of the infarct-related artery is termed “no reflow”. No reflow or slow flow occurs in 3 …

No-reflow phenomenon: maintaining vascular integrity

RA Kloner - Journal of cardiovascular pharmacology and …, 2011 - journals.sagepub.com
The no-reflow phenomenon relates to the inability to reperfuse regions of the myocardium
after ischemia, despite removal of the large epicardial coronary artery occlusion. The …

[PDF][PDF] The coronary no-reflow phenomenon: a review of mechanisms and therapies

E Eeckhout, MJ Kern - European heart journal, 2001 - doc.rero.ch
The phenomenon of no-reflow is defined as inadequate myocardial perfusion through a
given segment of the coronary circulation without angiographic evidence of mechanical …

No-reflow phenomenon and prognosis in patients with acute myocardial infarction

H Ito - Nature clinical practice Cardiovascular medicine, 2006 - nature.com
The rapid restoration of coronary flow to the jeopardized myocardium has become an
essential part of therapy after acute myocardial infarction. Despite an open infarct-related …

Myocardial no-reflow in humans

G Niccoli, F Burzotta, L Galiuto, F Crea - Journal of the American College of …, 2009 - jacc.org
In a variable proportion of patients presenting with ST-segment elevation myocardial
infarction, ranging from 5% to 50%, primary percutaneous coronary intervention achieves …

[PDF][PDF] No-reflow phenomenon: Achilles' heel of primary coronary angioplasty in acute myocardial infarction

J Kubica, M Koziński - Cardiology journal, 2008 - journals.viamedica.pl
Introduction of percutaneous coronary intervention (PCI) as a method of choice for the
treatment of patients with ST-segment elevation myocardial infarction has brought a marked …

Coronary no reflow

BG Schwartz, RA Kloner - Journal of molecular and cellular cardiology, 2012 - Elsevier
The no-reflow phenomenon has been studied extensively in the basic science laboratory
and has entered the clinical arena. No-reflow, which develops largely within the first 2h of …

No-reflow: again prevention is better than treatment

G Niccoli, RK Kharbanda, F Crea… - European heart …, 2010 - academic.oup.com
Primary percutaneous coronary intervention (PPCI) is the preferred reperfusion strategy for
treating acute ST-segment elevation myocardial infarction (STEMI). The main goals are to …

No-reflow phenomenon. A new target for therapy of acute myocardial infarction independent of myocardial infarct size

RA Kloner, W Dai, SL Hale - Journal of Cardiovascular …, 2018 - journals.sagepub.com
The no-reflow phenomenon is a failure to reperfuse portions of previously ischemic tissue
when patency of the large arteries perfusing an organ has been reestablished. This …