Early versus late profiles of inflammatory cytokines after mild traumatic brain injury and their association with neuropsychological outcomes

A Vedantam, J Brennan, HS Levin… - Journal of …, 2021 - liebertpub.com
Despite pre-clinical evidence for the role of inflammation in traumatic brain injury (TBI), there
is limited data on inflammatory biomarkers in mild TBI (mTBI). In this study, we describe the …

Inflammatory cytokines associate with neuroimaging after acute mild traumatic brain injury

KA Edwards, CL Pattinson, VA Guedes, J Peyer… - Frontiers in …, 2020 - frontiersin.org
Introduction: Elevated levels of blood-based proinflammatory cytokines are linked to acute
moderate to severe traumatic brain injuries (TBIs), yet less is known in acute mild (m) TBI …

Neuroinflammatory biomarkers for traumatic brain injury diagnosis and prognosis: A TRACK-TBI pilot study

JK Yue, FH Kobeissy, S Jain, X Sun… - Neurotrauma …, 2023 - liebertpub.com
The relationship between systemic inflammation and secondary injury in traumatic brain
injury (TBI) is complex. We investigated associations between inflammatory markers and …

Elevated serum levels of inflammation-related cytokines in mild traumatic brain injury are associated with cognitive performance

Y Sun, L Bai, X Niu, Z Wang, B Yin, G Bai… - Frontiers in …, 2019 - frontiersin.org
Mild traumatic brain injury (mTBI) is the most common neurological insult and leads to long-
lasting cognitive impairments. The immune system modulates brain functions and plays a …

[HTML][HTML] Blood-based biomarkers of inflammation in mild traumatic brain injury: A systematic review

K Visser, M Koggel, J Blaauw, HJ van der Horn… - Neuroscience & …, 2022 - Elsevier
Abstract VISSER, K., M. Koggel, J. Blaauw, HJvd Horn, B. Jacobs, and Jvd Naalt. Blood
based biomarkers of inflammation in mild traumatic brain injury: A systematic review …

Correlation between mild traumatic brain injury-induced inflammatory cytokines and emotional symptom traits: a systematic review

S Malik, O Alnaji, M Malik, T Gambale, MP Rathbone - Brain sciences, 2022 - mdpi.com
Both mild traumatic brain injuries (mTBI) and systemic injuries trigger a transient
neuroinflammatory response that result in similar clinical outcome. The ensuing physical …

Systemic inflammation persists the first year after mild traumatic brain injury: results from the prospective trondheim mild traumatic brain injury study

V Chaban, GJB Clarke, T Skandsen, R Islam… - Journal of …, 2020 - liebertpub.com
Innate immune activation has been attributed a key role in traumatic brain injury (TBI) and
successive morbidity. In mild TBI (mTBI), however, the extent and persistence of innate …

Pro-and anti-inflammatory biomarkers and traumatic brain injury outcomes: a review

T Rodney, N Osier, J Gill - Cytokine, 2018 - Elsevier
Abstract Traumatic Brain Injury (TBI) triggers a cascade of secondary biological and
physiological effects that are variable, depending on the severity, location, and complexity of …

The role of markers of inflammation in traumatic brain injury

T Woodcock, MC Morganti-Kossmann - Frontiers in neurology, 2013 - frontiersin.org
Within minutes of a traumatic impact, a robust inflammatory response is elicited in the injured
brain. The complexity of this post-traumatic squeal involves a cellular component …

Inflammatory cytokines associated with mild traumatic brain injury and clinical outcomes: a systematic review and meta-analysis

S Malik, O Alnaji, M Malik, T Gambale… - Frontiers in …, 2023 - frontiersin.org
Mild traumatic brain injuries (mTBIs) trigger a neuroinflammatory response, which leads to
perturbations in the levels of inflammatory cytokines, resulting in a distinctive profile. A …