IMPLICATIONS: Morphine sulfate attenuated hyperpermeability after hemorrhagic shock.
Our results suggest that instead of aggravating the inflammatory response after hemorrhagic …

The effect of analgesia on physiological systems has received little attention in trauma
research. Our aim was to examine the effect of two different analgesics, buprenorphine and …

To determine how hypoxemia (Hx) might alter muscle sympathetic nerve activity (MSNA)(
microneurography, peroneal nerve), norepinephrine (NE) levels, and vasoconstriction …

Hypotension after traumatic brain injury (TBI) has been associated with significant
reductions in cerebral blood flow (CBF) in experimental animals. In humans, posttraumatic …

Information has come forward recently from several sources which provides new insights
into the mechanisms that underlie the haemodynamic responses to acute blood loss. In …

Materials and Methods: There were 51 healthy participants who underwent a progressive
simulated hemorrhage to induce central hypovolemia by lower body negative pressure …

The regulation of compensatory hemodynamic, inflammatory, and metabolic counter-
regulatory responses to traumatic injury (trauma/hemorrhage [tx/hem]) and subsequent …

Previous studies from our laboratory indicate that acute but not chronic hypoxia decreases
the hemorrhage volume required to elicit reflex hypotension. Furthermore, chronically …

Trauma is the leading cause of death during the first four decades of life in the developed
countries. Its haemodynamic response underpins the patient's initial ability to survive, and …

Aim: To investigate the contribution of cerebral μ‐, κ‐and δ‐opioid receptors in causing the
hypotension, bradycardia and renal hypoperfusion evoked by haemorrhage. Methods: Adult …