International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults

G Goyal, A Tazi, RS Go, KL Rech… - Blood, The Journal …, 2022 - ashpublications.org
Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of
clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary …

Langerhans cell histiocytosis in adults: advances in pathophysiology and treatment

M Kobayashi, A Tojo - Cancer science, 2018 - Wiley Online Library
Langerhans cell histiocytosis (LCH) is a rare systemic disorder characterized by the
accumulation of CD 1a+/Langerin+ LCH cells and wide‐ranging organ involvement …

Langerhans cell histiocytosis

N Grana - Cancer Control, 2014 - journals.sagepub.com
Background Langerhans cell histiocytosis (LCH) is a rare histiocytic disorder of unknown
etiopathogenesis. Its clinical presentation is variable and ranges from isolated skin or bone …

Medical management of langerhans cell histiocytosis from diagnosis to treatment

J Donadieu, F Chalard, E Jeziorski - Expert opinion on …, 2012 - Taylor & Francis
Introduction: Langerhans cell histiocytosis (LCH) is a heterogeneous disease, involving the
accumulation of langerhans cells in various organs. The physician's perception of the …

Treatment outcomes and prognostic factors of patients with adult Langerhans cell histiocytosis

X Cao, M Duan, A Zhao, H Cai, J Chen… - American Journal of …, 2022 - Wiley Online Library
Adult Langerhans cell histiocytosis (LCH) remains poorly defined. We retrospectively
studied 266 newly diagnosed LCH patients to understand the clinical presentation …

Langerhans cell histiocytosis (LCH): guidelines for diagnosis, clinical work‐up, and treatment for patients till the age of 18 years

R Haupt, M Minkov, I Astigarraga… - Pediatric blood & …, 2013 - Wiley Online Library
These guidelines for the management of patients up to 18 years with Langerhans cell
histiocytosis (LCH) have been set up by a group of experts involved in the Euro Histio Net …

Management of adult patients with Langerhans cell histiocytosis: recommendations from an expert panel on behalf of Euro-Histio-Net

M Girschikofsky, M Arico, D Castillo, A Chu… - Orphanet journal of rare …, 2013 - Springer
Abstract Langerhans Cell Histiocytosis (LCH) is an orphan disease of clonal dendritic cells
which may affect any organ of the body. Most of the knowledge about the diagnosis and …

Langerhans cell histiocytosis: Version 2021

N Gulati, CE Allen - Hematological oncology, 2021 - Wiley Online Library
Children with Langerhnans cell histiocytosis (LCH) develop granulomatous lesions with
characteristic clonal CD207+ dendritic cells that can arise as single lesions or life …

Langerhans cell histiocytosis

C Rodriguez-Galindo, CE Allen - Blood, The Journal of the …, 2020 - ashpublications.org
Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors
that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ …

Langerhans cell histiocytosis in adults: more questions than answers?

M Arico - European Journal of Cancer, 2004 - Elsevier
Langerhans cell histiocytosis (LCH) may affect patients of any age but in adults the features
of this disease are still poorly defined. Most reports are based on single-specialty …