Secretion of the major mineralocorticoid aldosterone from the adrenal cortex is a tightly-
regulated process enabling this hormone to regulate sodium homeostasis and thereby …

Aldosterone secretion by the zona glomerulosa of the adrenal cortex is controlled by
circulating factors including the renin angiotensin system (RAS) and potassium …

Classically, aldosterone is synthesised in the adrenal zona glomerulosa and binds to
specific mineralocorticoid receptors located in the cytosol of target epithelial cells …

Aldosterone is a steroid hormone synthesized in and secreted from the outer layer of the
adrenal cortex, the zona glomerulosa. Aldosterone is responsible for regulating sodium …

The major physiological regulators of aldosterone production from the adrenal zona
glomerulosa are potassium and angiotensin II; other acute regulators include …

Although angiotensin II and potassium ion play the leading parts in the regulation of
aldosterone synthesis and secretion, various factors have recently been shown to act in …

Aldosterone is an important regulator of fluid and electrolyte balance. The capacity of the
adrenal gland to produce aldosterone is controlled by circulating levels of angiotensin II and …

Aldosterone, the endogenous ligand of the mineralocorticoid receptor (MR) in humans, is a
steroid hormone that regulates salt and water homeostasis. Recently, additional …

Aldosterone is one of the mineralocorticoids synthesized and secreted by the adrenal
glands, and it plays pivotal roles in regulating extracellular fluid volume and blood pressure …

Up to 15% of patients with essential hypertension have inappropriate regulation of
aldosterone; although only a minority have distinct adrenal tumors, recent evidence shows …