Belimumab: First targeted biological treatment for systemic lupus erythematosus

AK Dubey, SS Handu, S Dubey… - Journal of …, 2011 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder involving multiple
organs and having diverse clinical manifestations. Among the rheumatic diseases, it has …

[HTML][HTML] Belimumab (benlysta): a breakthrough therapy for systemic lupus erythematosus

R Lamore III, S Parmar, K Patel… - Pharmacy and …, 2012 - ncbi.nlm.nih.gov
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease that affects
approximately 250,000 Americans, with a female-to-male ratio of 10: 1. 1 SLE occurs …

Belimumab: A step forward in the treatment of systemic lupus erythematosus

R Depascale, M Gatto, M Zen, F Saccon… - Expert Opinion on …, 2021 - Taylor & Francis
ABSTRACT Introduction: Systemic Lupus Erythematosus (SLE) is a chronic B cell-mediated
autoimmune disease which can potentially involve several organs and systems. The …

Belimumab in systemic lupus erythematosus

A Vilas-Boas, SA Morais, DA Isenberg - RMD open, 2015 - rmdopen.bmj.com
Systemic lupus erythematosus (SLE) is one of the most challenging autoimmune disorders
with a complex pathophysiology and diverse clinical presentation. Many drugs have been …

Belimumab: a review in systemic lupus erythematosus

HA Blair, ST Duggan - Drugs, 2018 - Springer
Belimumab (Benlysta®) is a human immunoglobulin G1λ monoclonal antibody that inhibits
the binding of soluble B lymphocyte stimulator to B cells. It is the only biological agent …

Post-marketing experiences with belimumab in the treatment of SLE patients

AD Askanase, J Yazdany… - Rheumatic Disease …, 2014 - rheumatic.theclinics.com
Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect multiple
organ systems and whose hallmark is the production of autoantibodies. 1–3 A diagnosis of …

Belimumab in systemic lupus erythematosus (SLE): evidence-to-date and clinical usefulness

S Guerreiro Castro… - Therapeutic advances in …, 2017 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is a complex autoimmune rheumatic disease with
multiple presentations, whose management presents many challenges. Many disease …

Future prospects in biologic therapy for systemic lupus erythematosus

W Stohl - Nature Reviews Rheumatology, 2013 - nature.com
With the approval by the FDA in 2011 of a biologic agent (namely belimumab) for the
treatment of systemic lupus erythematosus (SLE), optimism abounds that additional biologic …

[HTML][HTML] Advances in drug therapy for systemic lupus erythematosus

DJ Wallace - BMC medicine, 2010 - Springer
Systemic lupus erythematosus (SLE) is an autoimmune disorder that afflicts 500,000 people
in the United States. There has not been a new SLE drug approved in the United States …

Biologics in the treatment of systemic lupus erythematosus

A Lateef, M Petri - Current opinion in rheumatology, 2010 - journals.lww.com
Biologics in the treatment of systemic lupus erythematosus : Current Opinion in Rheumatology
Biologics in the treatment of systemic lupus erythematosus : Current Opinion in Rheumatology …