Belimumab for systemic lupus erythematosus
Background Belimumab, the first biologic approved for the treatment of systemic lupus
erythematosus (SLE), has been shown to reduce autoantibody levels in people with SLE …
erythematosus (SLE), has been shown to reduce autoantibody levels in people with SLE …
Belimumab in systemic lupus erythematosus: a perspective review
JS Hui-Yuen, XQ Li… - Therapeutic Advances in …, 2015 - journals.sagepub.com
Belimumab (Benlysta®) is a fully humanized monoclonal antibody that inhibits B-lymphocyte
stimulator (also known as B cell activating factor of the tumor necrosis factor family) and was …
stimulator (also known as B cell activating factor of the tumor necrosis factor family) and was …
Belimumab in the treatment of systemic lupus erythematosus: high disease activity predictors of response
RF Van Vollenhoven, MA Petri, R Cervera… - Annals of the …, 2012 - ard.bmj.com
Objectives To identify factors that predict response to belimumab treatment in the phase 3
BLISS trials of autoantibody-positive systemic lupus erythematosus (SLE) and further …
BLISS trials of autoantibody-positive systemic lupus erythematosus (SLE) and further …
Safety and efficacy of belimumab to treat systemic lupus erythematosus in academic clinical practices
JS Hui-Yuen, A Reddy, J Taylor, X Li… - The Journal of …, 2015 - jrheum.org
Objective. To evaluate the use and efficacy of belimumab in academic practices. Belimumab
is a human monoclonal antibody that inhibits soluble B lymphocyte stimulator and has been …
is a human monoclonal antibody that inhibits soluble B lymphocyte stimulator and has been …
Real-world effectiveness of belimumab in systemic lupus erythematosus: a systematic literature review
SP Huang, SJ Snedecor, S Nanji, E Lloyd… - Rheumatology and …, 2022 - Springer
Introduction Belimumab is a recombinant human monoclonal antibody that binds to soluble
B-lymphocyte stimulator and inhibits its biological activity. Since receiving approvals for the …
B-lymphocyte stimulator and inhibits its biological activity. Since receiving approvals for the …
Long‐term safety profile of belimumab plus standard therapy in patients with systemic lupus erythematosus
JT Merrill, EM Ginzler, DJ Wallace… - Arthritis & …, 2012 - Wiley Online Library
Objective To evaluate the safety profile of long‐term belimumab therapy combined with
standard therapy for systemic lupus erythematosus (SLE) in patients with active disease …
standard therapy for systemic lupus erythematosus (SLE) in patients with active disease …
Lupus: novel therapies in clinical development
PK Chugh - European Journal of Internal Medicine, 2012 - Elsevier
There have been significant advancements in understanding the immunopathogenesis of
systemic lupus erythematosus. However, the developments in therapeutics have been rather …
systemic lupus erythematosus. However, the developments in therapeutics have been rather …
Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose …
M van Schaik, EJ Arends, D Soonawala, E van Ommen… - Trials, 2022 - Springer
Background Belimumab, an anti-B-cell activating factor antibody, is approved for the
treatment of auto-antibody positive systemic lupus erythematosus with a high degree of …
treatment of auto-antibody positive systemic lupus erythematosus with a high degree of …
Systemic lupus erythematosus: still a challenge for physicians
AA Bengtsson, L Rönnblom - Journal of internal medicine, 2017 - Wiley Online Library
Systemic lupus erythematosus (SLE) has a complex clinical picture, and a number of defects
in the immune system have been described in patients with the disease. Most organs can be …
in the immune system have been described in patients with the disease. Most organs can be …
Real-world effectiveness of belimumab in the treatment of systemic lupus erythematosus: pooled analysis of multi-country data from the OBSErve studies
CE Collins, J Cortes-Hernández, MA Garcia… - Rheumatology and …, 2020 - Springer
Introduction The real-world effectiveness of belimumab for systemic lupus erythematosus
(SLE) in six countries was evaluated in the OBSErve program. The aim of this post hoc …
(SLE) in six countries was evaluated in the OBSErve program. The aim of this post hoc …