Diffuse optical tomography has demonstrated significant potential for clinical utility in the
diagnosis and prognosis of breast cancer, and its use in combination with other structural …

Abstract Diffuse Optical Tomography and Spectroscopy permit measurement of important
physiological parameters non-invasively through~ 10 cm of tissue. I have applied these …

Three‐dimensional diffuse optical tomography (DOT) of breast requires large data sets for
even modest resolution (1 cm). We present a hybrid DOT system that combines a limited …

A handheld scanning probe based on broadband Diffuse Optical Spectroscopy (DOS) was
used in combination with dynamic contrast enhanced MRI (DCE-MRI) to quantitatively …

Abstract Diffuse Optical Tomography (DOT) in the Near Infrared NIR offers the potential to
perform non-invasive three-dimensional quantified imaging of large-organs in vivo. The …

Purpose: The authors introduce a state‐of‐the‐art all‐optical clinical diffuse optical
tomography (DOT) imaging instrument which collects spatially dense, multispectral …

The instrument development and design of a prototype frequency-domain optical imaging
device for breast cancer detection is described in detail. This device employs radio …

We present a novel methodology for combining breast image data obtained at different
times, in different geometries, and by different techniques. We combine data based on …

The authors investigate the performance of diffuse optical tomography to image highly
heterogeneous media, such as breast tissue, as a function of background heterogeneity. To …

Purpose A NIR tomography system that combines frequency domain (FD) and continuous
wave (CW) measurements was used to image normal and malignant breast tissues …