The effects of Aripiprazole and olanzapine on pupillary light reflex and its relationship with Pharmacogenetics in a randomized Multiple‐Dose trial

D Koller, M Saiz‐Rodríguez, P Zubiaur… - British journal of …, 2020 - Wiley Online Library
Aims Pupillography is a noninvasive and cost‐effective method to determine autonomic
nerve activity. Genetic variants in cytochrome P450 (CYP), dopamine receptor (DRD2 …

Effects of aripiprazole on pupillometric parameters related to pharmacokinetics and pharmacogenetics after single oral administration to healthy subjects

D Koller, C Belmonte, R Lubomirov… - Journal of …, 2018 - journals.sagepub.com
Background: Pupillometry is used for the detection of autonomic dysfunction related to
numerous diseases and drug administration. Genetic variants in cytochrome P450 …

Metabolic effects of aripiprazole and olanzapine multiple-dose treatment in a randomised crossover clinical trial in healthy volunteers: association with …

D Koller, S Almenara, G Mejía, M Saiz-Rodríguez… - Advances in …, 2021 - Springer
Introduction Aripiprazole and olanzapine are atypical antipsychotics. Both drugs can induce
metabolic changes; however, the metabolic side effects produced by aripiprazole are more …

Impact of CYP2C19 phenotypes on escitalopram metabolism and an evaluation of pupillometry as a serotonergic biomarker

L Noehr-Jensen, ST Zwisler, F Larsen… - European journal of …, 2009 - Springer
Purpose To investigate the impact of cytochrome P450 2C19 (CYP2C19) phenotypes on
escitalopram metabolism and to evaluate pupillometry as a serotonergic biomarker …

Effects of aripiprazole on circadian prolactin secretion related to pharmacogenetics in healthy volunteers

D Koller, C Belmonte, M Saiz‐Rodríguez… - Basic & clinical …, 2020 - Wiley Online Library
Aripiprazole treatment in schizophrenic patients was previously associated with lower or
normalized prolactin levels. Genetic variants in cytochrome P450 (CYP)(CYP2D6) …

Effects of DRD2 and CYP2D6 genotypes on delta EEG power response to aripiprazole in healthy male volunteers: a preliminary study

E Kim, KS Yu, JY Cho, YW Shin, SY Yoo… - Human …, 2006 - Wiley Online Library
The aim of the present study was to evaluate the effects of polymorphisms in dopamine D2
receptor (DRD2) and cytochrome P450 (CYP) 2D6 genes on delta EEG power response to …

Comparison of the effects of clonidine and yohimbine on pupillary diameter at different illumination levels

MA Phillips, E Szabadi… - British journal of clinical …, 2000 - Wiley Online Library
Aims To evaluate the pupillary effects of single doses of the α2‐adrenoceptor agonist
clonidine and the α2‐adrenoceptor antagonist yohimbine under several illumination …

Genetic polymorphisms associated with the pharmacokinetics, pharmacodynamics and adverse effects of olanzapine, aripiprazole and risperidone

P Soria-Chacartegui, G Villapalos-García… - Frontiers in …, 2021 - frontiersin.org
Olanzapine, aripiprazole and risperidone are atypical antipsychotics or neuroleptics widely
used for schizophrenia treatment. They induce various adverse drug reactions depending …

Pupillometry in psychopharmacologic experiments

J Grünberger, L Linzmayer, H Cepko… - Arzneimittel …, 1986 - europepmc.org
Considering data of various clinical pharmacological studies, in which computer-assisted
pupillometry was utilized, we investigated the following questions: What are the effects of …

Aripiprazole induced transient myopia: a case report and review of literature

AG Nair, AG Nair, RJ George, J Biswas… - Cutaneous and Ocular …, 2012 - Taylor & Francis
Aripiprazole is a drug belonging to the group of atypical antipsychotics. Ocular side effects of
aripiprazole are rare. We report a case of transient myopia in a 33-year-old male who was …