Our objective was to determine the influence of a high-fat diet (HFD) on fasting and
postprandial skeletal muscle substrate metabolism in endurance-trained (ET) compared with …

Ageing and obesity independently have been shown to significantly impair isolated muscle
contractile properties, though their synergistic effects are poorly understood. We uniquely …

We determined the interaction of diet and exercise-training intensity on membrane
phospholipid fatty acid (FA) composition in skeletal muscle from 36 female Sprague-Dawley …

Purpose To investigate the effects of endurance training on the content of ω-3
polyunsaturated fatty acids (PUFAs) and their distribution among lipid classes in skeletal …

Muscle lipid increases with high-fat feeding and diabetes. In trained athletes, increased
muscle lipid is not associated with insulin resistance, a phenomenon known as the athlete's …

Insulin action and glucose disposal are enhanced by exercise, yet the mechanisms involved
remain imperfectly understood. While the causes of skeletal muscle insulin resistance also …

Obesity and aging are characterized by decreased insulin sensitivity (IS) and muscle protein
synthesis. Intramuscular ceramide accumulation has been implicated in insulin resistance …

Metabolic syndrome components, including obesity, dyslipidemia and impaired glucose
homeostasis, become a major public health issue. Muscles play a predominant role in …

Age-related loss of skeletal muscle mass results in a reduction in metabolically active tissue
and has been related to the onset of obesity and sarcopenia. Although the causes of muscle …

Our aim was to compare and combine 3 nutritional strategies to slow down the age-related
loss of muscle mass in healthy old rats: 1) increase protein intake, which is likely to stimulate …