Objective Stem cell transplantation is a promising strategy with great potential to treat
Parkinson's disease (PD). Nevertheless, improving the cell delivery route and optimising …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. It affects the locomotor system, leading to a final severe disability through …

Bone marrow-derived neural stem cells (NSCs) are ideal cells for cellular therapy because
of their therapeutic potential for repairing and regenerating damaged neurons. However, the …

Intranasal mesenchymal stem cells (MSCs) delivery is a non-invasive method that has
received interests for treatment of neurodegenerative diseases, such as multiple sclerosis …

Bone marrow-derived neural stem cells (BM-NSCs) have shed light on novel therapeutic
approaches for PD with the potential to halt or even reverse disease progression. Various …

Parkinson's disease (PD) is the most common movement disorder, characterized by the
progressive loss of dopaminergic neurons from the nigrostriatal system. Currently, there is …

Previous studies have shown that bone marrow mesenchymal stem cells (BMSCs)
engraftment could alleviate motor dysfunction in parkinsonian animal models, but with …

The potential value of cerebral dopamine neurotrophic factor (CDNF) in treating Parkinson's
disease (PD) remains controversial. To evaluate the therapeutic effects of CDNF-expressing …

Multiple sclerosis (MS) is an inflammatory and demyelinating disease of the central nervous
system (CNS) that leads to disability in middle‐aged individuals. High rates of apoptosis and …

In view of the rapid preclinical development of cell-based therapies for neurodegenerative
disorders, traumatic brain injury, and tumors, the safe and efficient delivery and targeting of …