Colorectal cancer is the third most common cancer diagnosed worldwide. Although
epidemiology data show a marked variability around the world, its overall incidence rate …

Colorectal cancer (CRC) has a great impact on the world population. With increasing
frequency, CRC is described according to the presenting phenotype, based on its molecular …

Background Colorectal cancer is typically a condition of older patients with only 10%
diagnosed under the age of 50 years. Often, diagnosis is delayed, but certain factors such as …

Early-onset colorectal cancer (EOCRC), defined as that diagnosed before the age of 50,
accounts for 10–12% of all new colorectal cancer (CRC) diagnoses. Epidemiological data …

AIM: To characterize clinicopathological and familial features of early-onset colorectal
cancer (CRC) and compare features of tumors with and without microsatellite instability …

Colorectal cancer (CRC) is one of the leading causes of cancer related mortality worldwide.
Although young-onset CRC raises the possibility of a hereditary component, hereditary CRC …

Sporadic early onset colorectal carcinoma (EOCRC) which has by definition no identified
hereditary predisposition is a growing problem that remains poorly understood. Molecular …

Treatment of young adults with colorectal cancer (CRC) represents an unmet clinical need,
especially as diagnosis in this population might lead to the greatest loss of years of life …

Methods In this retrospective case-case study, patients were prospectively enrolled from
2015 to 2018. We collected clinical features (age, sex, time from symptom onset to …

Simple Summary Early-onset colorectal cancer is increasing in incidence in the United
States, and it is expected to more than double in the next 10 years. There are many risk …