The canonical function of the Hippo signaling pathway is the regulation of organ growth.
How this pathway controls cell-fate determination is less well understood. Here, we identify a …

The Hippo pathway is a conserved signaling network that regulates organ growth and cell
fate. One such cell fate decision is that of R8 photoreceptor cells in the Drosophila eye …

The evolutionarily conserved Hippo signaling pathway is known to regulate cell proliferation
and maintain tissue homeostasis during development. We found that activation of Yorkie …

The Hippo pathway has emerged as a conserved signaling pathway that is essential for the
proper regulation of organ growth in Drosophila and vertebrates. Although the mechanisms …

Hippo signaling is an important regulator of tissue size, but it also has a lesser-known role in
tissue morphogenesis. Here we use the Drosophila pupal eye to explore the role of the …

Organ growth is fundamental to animal development. One of major mechanisms for growth
control is mediated by the conserved Hippo signaling pathway initially identified in …

Signaling pathways are reused for multiple purposes in plant and animal development. The
Hippo pathway in mammals and Drosophila coordinates proliferation and apoptosis via the …

The accurate control of cell proliferation and survival is critical for animal development. The
Hippo tumor suppressor pathway regulates both of these parameters by controlling the …

The development of a functional organ requires not only patterning mechanisms that confer
proper identities to individual cells, but also growth-regulatory mechanisms that specify the …

The Hippo pathway is an evolutionarily conserved signaling network that regulates organ
size, cell fate, and tumorigenesis. In the context of organ size control, the pathway …