Background and Aims. The gut microbiome, an aggregate genome of trillions of
microorganisms residing in the human gastrointestinal tract, is now known to play a critical …

A mutualistic relationship between the composition, function and activity of the gut
microbiota (GM) and the host exists, and the alteration of GM, sometimes referred as …

Background & Aims Altered interactions between the mucosal immune system and intestinal
microbiota contribute to pathogenesis of inflammatory bowel diseases (IBD). It is not clear …

Abstract Knowledge about associations between changes in the structure and/or function of
intestinal microbes (the microbiota) and the pathogenesis of various diseases is expanding …

Little was known about the development of the gastrointestinal (GI) tract microbiota, until
recently, because of difficulties in obtaining sufficient sequence information from enough …

The prevalence of colon-associated diseases has increased significantly over the past
several decades, as evidenced by accumulated literature on conditions such as Crohn's …

Background Global prescription drug use has been increasing continuously for decades.
The gut microbiome, a key contributor to health status, can be altered by prescription drug …

Considered as an essential “metabolic organ”, intestinal microbiota plays a key role in
human health and the predisposition to diseases. It is an aggregate genome of trillions of …

The influence of resident gut microbes on xenobiotic metabolism has been investigated at
different levels throughout the past five decades. However, with the advance in sequencing …

The recent increase in our knowledge of human gut microbiota has changed our view on
antibiotics. Antibiotics are, indeed, no longer considered only beneficial, but also potentially …