While mortality from overt ischaemic heart disease is falling, that from heart failure is
increasing and reaching epidemic proportions. 1 Although an aging population is partly …

Over the last 50 years, studies investigating the pathogenesis of left ventricular dysfunction
have resulted in many potential therapeutic targets being identified and novel classes of …

Heart failure secondary to myocardial infarction (MI) remains a major source of morbidity
and mortality. Long-term outcome after MI can be largely be defined in terms of its impact on …

During the past two decades, it has become increasingly well acknowledged that a large,
transmural acute myocardial infarction (AMI) may result in complex alterations in the …

In the past decades, myocardial infarction periacute mortality markedly declined since
coronary reperfusion therapy has been adopted. Despite immediate benefits of coronary …

Due to continuous remodelling myocardial dysfunction is a progressive condition. Even if the
initial event is so mild that it causes no immediate cardiac dysfunction (eg a small …

This review briefly highlights the major mechanisms of left ventricular (LV) remodeling
following myocardial infarction in heart failure and presents novel strategies to limit infarct …

Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

Objectives This study sought to investigate the impact of post-infarct left ventricular (LV)
remodeling on outcomes in the contemporary era. Background LV remodeling after ST …

Most patients survive acute myocardial infarction (MI). Yet this encouraging development
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …