P-cresyl sulfate and indoxyl sulfate are strongly associated with cardiovascular events and
all-cause mortality in chronic kidney disease (CKD). This randomized controlled trial was …

Background Beside the phosphate binding effect, non-calcium non-aluminum phosphate
binder, namely sevelamer hydrochloride (SH), has many other effects in dialysis patients. It …

An increasing body of experimental and clinical evidence suggests that p-cresol sulfate and
indoxyl sulfate contribute to the high cardiovascular burden in patients with chronic kidney …

The number of chronic kidney disease (CKD) patients and related adverse outcomes has
dramatically increased worldwide in the past decade. Therefore, numerous experimental …

Background Hyperphosphatemia control is a major issue in hemodialysis patients. Both
sevelamer and nicotinamide are prescribed for this purpose. In addition, they exert …

Hyperphosphatemia is considered as an independent risk factor for surrogate clinical
endpoints like vascular calcification (VC) and bone disease, or hard clinical outcomes like …

Background Indoxyl sulfate (IS) and p-cresyl sulfate (PCS) are protein-bound uremic toxins
that increase in the sera of patients with chronic kidney disease (CKD), and are not …

OBJECTIVE: There is a growing interest in the potential anti-inflammatory properties of
sevelamer hydrochloride, a commonly used phosphate binder for patients with chronic …

The protein-bound uremic toxins para-cresyl sulfate (pCS) and indoxyl sulfate (IS) are
associated with cardiovascular disease in chronic renal failure, but the effect of different …

Background and Aims P-cresyl sulfate (PCS) and indoxyl sulfate (IS) were not only novel but
essential factors associated with cardiovascular disease and mortality in patients with …