COPD maintenance therapy with tiotropium/olodaterol compared with tiotropium: an analysis in the absence of additional ICS therapy
PMA Calverley, A Hoz, W Xue… - COPD: Journal of …, 2020 - Taylor & Francis
Abstract The American Thoracic Society guidelines recommend long-acting β2-agonist
(LABA)/long-acting muscarinic antagonist (LAMA) dual bronchodilation over LAMA or LABA …
(LABA)/long-acting muscarinic antagonist (LAMA) dual bronchodilation over LAMA or LABA …
Tiotropium as essential maintenance therapy in COPD
M Decramer - European Respiratory Review, 2006 - Eur Respiratory Soc
Over the past decade, several large-scale clinical trials have been performed to assess the
impact of pharmacological treatments on patient-centred outcomes such as dyspnoea …
impact of pharmacological treatments on patient-centred outcomes such as dyspnoea …
Efficacy of tiotropium/olodaterol compared with tiotropium as a first-line maintenance treatment in patients with COPD who are naïve to LAMA, LABA and ICS: pooled …
R Buhl, A de la Hoz, W Xue, D Singh, GT Ferguson - Advances in Therapy, 2020 - Springer
Introduction The efficacy of tiotropium/olodaterol compared with tiotropium in patients with
chronic obstructive pulmonary disease (COPD) has been demonstrated in a large clinical …
chronic obstructive pulmonary disease (COPD) has been demonstrated in a large clinical …
Tiotropium as a first maintenance drug in COPD: secondary analysis of the UPLIFT® trial
The aim of the present study was investigate the long-term effect of tiotropium as first
maintenance respiratory medication in chronic obstructive pulmonary disease (COPD). A 4 …
maintenance respiratory medication in chronic obstructive pulmonary disease (COPD). A 4 …
Effects of tiotropium + olodaterol versus tiotropium or placebo by COPD disease severity and previous treatment history in the OTEMTO® studies
D Singh, M Gaga, O Schmidt, L Bjermer, L Grönke… - Respiratory …, 2016 - Springer
Background As lung function declines rapidly in the early stages of chronic obstructive
pulmonary disease (COPD), the effects of bronchodilators in patients with moderate disease …
pulmonary disease (COPD), the effects of bronchodilators in patients with moderate disease …
Long-term treatment benefits with tiotropium in COPD patients with and without short-term bronchodilator responses
D Tashkin, S Kesten - Chest, 2003 - Elsevier
Objectives: To determine whether long-term symptomatic improvement occurs in COPD
patients with maintenance bronchodilator therapy despite a nonsignificant short-term …
patients with maintenance bronchodilator therapy despite a nonsignificant short-term …
[HTML][HTML] Tiotropium in COPD patients not previously receiving maintenance respiratory medications
SG Adams, A Anzueto, DD Briggs Jr, SS Menjoge… - Respiratory …, 2006 - Elsevier
INTRODUCTION: Use of maintenance bronchodilator therapy is currently recommended in
symptomatic patients with Chronic obstructive pulmonary disease (COPD) and in those with …
symptomatic patients with Chronic obstructive pulmonary disease (COPD) and in those with …
[引用][C] Tiotropium plus olodaterol fixed-dose combination therapy provides lung function benefits when compared with tiotropium alone, irrespective of prior treatment …
R Buhl, R Abrahams, L Gronke, L Korducki… - D36. ALL TOGETHER …, 2015 - atsjournals.org
Methods In the studies, 2124 patients had not received prior LABD treatment (T+ O n= 426; T
n= 454) and 3038 patients had (T+ O n= 603, T n= 579; 60.6% LAMA, 78.8% LABA) …
n= 454) and 3038 patients had (T+ O n= 603, T n= 579; 60.6% LAMA, 78.8% LABA) …
Efficacy and safety of tiotropium + olodaterol maintenance treatment in patients with COPD in the TONADO® and OTEMTO® studies: a subgroup analysis by age
GT Ferguson, JP Karpel, E Clerisme-Beaty… - … Journal of Chronic …, 2016 - Taylor & Francis
Background Increasing age is associated with poor prognosis in patients with COPD.
Objective This analysis from the replicate Phase III OTEMTO® and TONADO® studies …
Objective This analysis from the replicate Phase III OTEMTO® and TONADO® studies …
Efficacy of Once-Daily Tiotropium and Olodaterol Maintenance Treatment for COPD: Patient-Reported Outcomes
F Maltais, L Groenke, L Korducki, R Buhl - Chest, 2015 - journal.chestnet.org
PURPOSE: Chronic obstructive pulmonary disease (COPD) is a highly symptomatic and
debilitating condition. The efficacy and safety of a new once-daily (QD) maintenance …
debilitating condition. The efficacy and safety of a new once-daily (QD) maintenance …