[HTML][HTML] The relationship between amyloid-beta and brain capillary endothelial cells in Alzheimer's disease
YL Zhang, J Wang, ZN Zhang, Q Su… - Neural Regeneration …, 2022 - journals.lww.com
Neurovascular dysfunction, as an integral part of Alzheimer's disease, may have an
important influence on the onset and progression of chronic neurodegenerative processes …
important influence on the onset and progression of chronic neurodegenerative processes …
Neurovascular dysfunction and faulty amyloid β-peptide clearance in Alzheimer disease
AP Sagare, RD Bell… - Cold Spring …, 2012 - perspectivesinmedicine.cshlp.org
Neurovascular dysfunction is an integral part of Alzheimer disease (AD). Changes in the
brain vascular system may contribute in a significant way to the onset and progression of …
brain vascular system may contribute in a significant way to the onset and progression of …
Neurovascular defects and faulty amyloid-β vascular clearance in Alzheimer's disease
AP Sagare, RD Bell, BV Zlokovic - Journal of Alzheimer's …, 2013 - content.iospress.com
The evidence that neurovascular dysfunction is an integral part of Alzheimer's disease (AD)
pathogenesis has continued to emerge in the last decade. Changes in the brain vasculature …
pathogenesis has continued to emerge in the last decade. Changes in the brain vasculature …
Neurovascular mechanisms and blood–brain barrier disorder in Alzheimer's disease
RD Bell, BV Zlokovic - Acta neuropathologica, 2009 - Springer
Vascular dysfunction has a critical role in Alzheimer's disease (AD). Recent data from brain
imaging studies in humans and animal models suggest that cerebrovascular dysfunction …
imaging studies in humans and animal models suggest that cerebrovascular dysfunction …
Traffic jam at the blood–brain barrier promotes greater accumulation of Alzheimer's disease amyloid-β proteins in the cerebral vasculature
EK Agyare, SR Leonard, GL Curran, CC Yu… - Molecular …, 2013 - ACS Publications
Amyloid-β (Aβ) deposition in the brain vasculature results in cerebral amyloid angiopathy
(CAA), which occurs in about 80% of Alzheimer's disease (AD) patients. While Aβ42 …
(CAA), which occurs in about 80% of Alzheimer's disease (AD) patients. While Aβ42 …
Blood-brain-barrier models for the investigation of transporter-and receptor-mediated amyloid-β clearance in Alzheimer's disease
T Pflanzner, CR Kuhlmann… - Current Alzheimer …, 2010 - ingentaconnect.com
Alzheimer's disease (AD) is the most common form of dementia in the elderly with more than
26 million people worldwide living with the disease. Besides the main neuropathological …
26 million people worldwide living with the disease. Besides the main neuropathological …
[HTML][HTML] The role of amyloid beta clearance in cerebral amyloid angiopathy: more potential therapeutic targets
X Qi, J Ma - Translational neurodegeneration, 2017 - Springer
Cerebral amyloid angiopathy (CAA) is characterized by the deposition of amyloid β-protein
(Aβ) in the leptomeningeal and cortical blood vessels, which is an age-dependent risk factor …
(Aβ) in the leptomeningeal and cortical blood vessels, which is an age-dependent risk factor …
Modulation of amyloid-β 1–40 transport by ApoA1 and ApoJ across an in vitro model of the blood-brain barrier
C Merino-Zamorano… - Journal of …, 2016 - content.iospress.com
Amyloid-β (Aβ) accumulation in Alzheimer's disease (AD) and cerebral amyloid angiopathy
(CAA) is likely caused by the impairment of its brain clearance that partly occurs through the …
(CAA) is likely caused by the impairment of its brain clearance that partly occurs through the …
[HTML][HTML] Advances in Amyloid-β Clearance in the Brain and Periphery: Implications for Neurodegenerative Diseases
R Ullah, EJ Lee - Experimental Neurobiology, 2023 - ncbi.nlm.nih.gov
This review examines the role of impaired amyloid-β clearance in the accumulation of
amyloid-β in the brain and the periphery, which is closely associated with Alzheimer's …
amyloid-β in the brain and the periphery, which is closely associated with Alzheimer's …
Aβ42 production in brain capillary endothelial cells after oxygen and glucose deprivation
A Bulbarelli, E Lonati, A Brambilla, A Orlando… - Molecular and Cellular …, 2012 - Elsevier
Although the diverse triggers of AD are still under debate, the hypothesis of the contribution
of cerebrovascular deficiencies has emerged in recent years. Cerebrovascular dysfunction …
of cerebrovascular deficiencies has emerged in recent years. Cerebrovascular dysfunction …