The repertoire of genetic alterations in salivary duct carcinoma including a novel HNRNPH3-ALK rearrangement

S Dogan, CKY Ng, B Xu, R Kumar, L Wang… - Human pathology, 2019 - Elsevier
Salivary duct carcinoma (SDC) is a rare, aggressive malignancy with limited treatment
options and poor outcome. Twenty-nine primary resected SDC, including 15 SDC de novo …

Lacrimal gland adenocarcinoma responding to checkpoint inhibition and androgen deprivation

A Bulbul - Oxford Medical Case Reports, 2018 - academic.oup.com
Although the histologically diverse classification of salivary gland tumors can be successfully
applied to the epithelial lacrimal gland neoplasms, it is not clear whether the molecular …

[引用][C] Sequential HER2-targeted therapy in salivary ductal carcinoma with HER2/neu overexpression and a concomitant ERBB2 mutation

D Almquist, JM Umakanthan, AK Ganti - JCO Precision Oncology, 2018 - ascopubs.org
Salivary duct carcinoma (SDC) is a rare malignancy arising from the major and minor
salivary glands. 1, 2 Though curative intent surgery followed by radiation is the treatment of …

Frequent PTEN loss and differential HER2/PI3K signaling pathway alterations in salivary duct carcinoma: Implications for targeted therapy

P Saintigny, Y Mitani, KB Pytynia, R Ferrarotto… - Cancer, 2018 - Wiley Online Library
BACKGROUND Patients with advanced primary and recurrent salivary duct carcinoma
(SDC), a rare and lethal malignancy, have limited therapeutic options. Novel small‐molecule …

Profiling of 149 salivary duct carcinomas, carcinoma ex pleomorphic adenomas, and adenocarcinomas, not otherwise specified reveals actionable genomic …

K Wang, JS Russell, JD McDermott, JA Elvin… - Clinical cancer …, 2016 - AACR
Purpose: We sought to identify genomic alterations (GA) in salivary gland adenocarcinomas,
not otherwise specified (NOS), salivary duct carcinomas (SDC), carcinoma ex pleomorphic …

Androgen receptor immunohistochemistry in salivary duct carcinoma: a retrospective study of 188 cases focusing on tumoral heterogeneity and temporal concordance

B Xu, S Dogan, MRH Al Rasheed, R Ghossein… - Human pathology, 2019 - Elsevier
Salivary duct carcinoma (SDC) is a high-grade salivary gland carcinoma that is associated
with frequent metastasis and poor outcome. Androgen receptor (AR) immunoexpression in …

Expression of PTEN, Androgen Receptor, HER2/neu, Cytokeratin 5/6, Estrogen Receptor-Beta, HMGA2, and PLAG1 in Salivary Duct Carcinoma

L Liang, MD Williams, D Bell - Head and neck pathology, 2019 - Springer
Salivary duct carcinoma (SDC) is an aggressive neoplasm that resembles high-grade
invasive ductal carcinoma of the breast. It can develop de novo or from the malignant …

HER2 expression in salivary gland carcinomas: dependence on histological subtype

B Glisson, AD Colevas, R Haddad, J Krane… - Clinical Cancer …, 2004 - AACR
Purpose: Previous evaluation of HER2 overexpression in salivary gland cancers indicated
an incidence varying between 7 and 56%, with no clear difference among three …

Salivary duct carcinomas can be classified into luminal androgen receptor‐positive, HER2 and basal‐like phenotypes

S Di Palma, RHW Simpson, C Marchiò… - …, 2012 - Wiley Online Library
Di Palma S, Simpson RHW, Marchiò C, Skálová A, Ungari M, Sandison A, Whitaker S, Parry
S & Reis‐Filho JS (2012) Histopathology 61, 629–643 Salivary duct carcinomas can be …

Overexpression of PD-L2 is associated with shorter relapse-free survival in patients with malignant salivary gland tumors

H Chang, JS Kim, YJ Choi, JG Cho, JS Woo… - OncoTargets and …, 2017 - Taylor & Francis
Objectives PD-1/PD-L1 and CTLA-4 have been investigated and are thought to play an
important role in tumor evasion. This study aimed to investigate expression patterns of …