Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months

DL King, GW Arendash - Physiology & behavior, 2002 - Elsevier
Behavioral characterization of Alzheimer's disease (AD) transgenic models over multiple
time points during aging has been largely inadequate, usually being limited to one or two …

Intra-and intertask relationships in a behavioral test battery given to Tg2576 transgenic mice and controls

GW Arendash, DL King - Physiology & behavior, 2002 - Elsevier
Several transgenic mouse models for Alzheimer's disease (AD) that develop β-amyloid
deposition have recently been advanced, including the Tg2576 mouse. Thorough …

Age-dependent and-independent behavioral deficits in Tg2576 mice

RMJ Deacon, LL Cholerton, K Talbot… - Behavioural brain …, 2008 - Elsevier
The Tg2576 mouse model of excessive cerebral β-amyloid deposition is now more than a
decade old, yet consensus as to its exact characteristics and utility as a model of Alzheimer's …

Aspects of spatial memory and behavioral disinhibition in Tg2576 transgenic mice as a model of Alzheimer's disease

E Ognibene, S Middei, S Daniele, W Adriani… - Behavioural brain …, 2005 - Elsevier
Transgenic mouse models of Alzheimer's disease (AD) have been recently advanced.
Tg2576 mice have been shown to develop progressive β-amyloid (Aβ) neuritic plaques and …

Severe motor neuron degeneration in the spinal cord of the Tg2576 mouse model of Alzheimer disease

JS Seo, YH Leem, KW Lee, SW Kim… - Journal of …, 2010 - content.iospress.com
The transgenic mouse Tg2576 is widely used as a murine model of Alzheimer's disease
(AD) and exhibits plaque pathogenesis in the brain and progressive memory impairments …

Aged Tg2576 mice are impaired on social memory and open field habituation tests

RMJ Deacon, E Koros, KD Bornemann… - Behavioural brain …, 2009 - Elsevier
In a previous publication [Deacon RMJ, Cholerton LL, Talbot K, Nair-Roberts RG,
Sanderson DJ, Romberg C, et al. Age-dependent and-independent behavioral deficits in …

Increase of locomotor activity underlying the behavioral disinhibition in tg2576 mice.

FJ Gil-Bea, B Aisa, R Schliebs… - Behavioral …, 2007 - psycnet.apa.org
The transgenic Tg2576 mouse is a widely used animal model that develops some of the
cognitive and neuropathological deteriorations observed in patients suffering Alzheimer's …

Task-dependent learning and memory deficits in the TgF344-AD rat model of Alzheimer's disease: three key timepoints through middle-age in females

VE Bernaud, HL Bulen, VL Peña, SV Koebele… - Scientific reports, 2022 - nature.com
The TgF344 rat model of Alzheimer's disease (AD) provides a comprehensive
neuropathology presentation, with age-dependent development of tau tangles, amyloid-beta …

Activity changes and marked stereotypic behavior precede Aβ pathology in TgCRND8 Alzheimer mice

O Ambrée, C Touma, N Görtz, K Keyvani, W Paulus… - Neurobiology of …, 2006 - Elsevier
Alzheimer's disease (AD) is not only characterized by cognitive decline and
neuropathological changes, but also by non-cognitive behavioral symptoms like …

A comprehensive behavioral test battery to assess learning and memory in 129S6/Tg2576 mice

A Wolf, B Bauer, EL Abner, T Ashkenazy-Frolinger… - PloS one, 2016 - journals.plos.org
Transgenic Tg2576 mice overexpressing human amyloid precursor protein (hAPP) are a
widely used Alzheimer's disease (AD) mouse model to evaluate treatment effects on amyloid …