[HTML][HTML] Neuroprotective effects of protocatechuic aldehyde through PLK2/p-GSK3β/Nrf2 signaling pathway in both in vivo and in vitro models of Parkinson's disease

C Guo, J Zhu, J Wang, J Duan, S Ma, Y Yin… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Mitochondrial dysfunction and oxidative damage are closely related to the pathogenesis of
Parkinson's disease (PD). The pharmacological mechanism of protocatechuic aldehyde …

Neuroprotective effect of echinacoside in subacute mouse model of Parkinson's disease

Y Liang, C Chen, B Xia, W Wu, J Tang… - BioMed Research …, 2019 - Wiley Online Library
Objective. To study the protective effect of Echinacoside for 1‐methyl‐4‐phenyl‐1, 2, 3, 6‐
tetrahydropyridine (MPTP) induced dopaminergic (DA) neurons injury in the subacute …

Protective effect of arctigenin against MPP+ and MPTP-induced neurotoxicity

D Li, Q Liu, D Jia, D Dou, X Wang, T Kang - Planta medica, 2014 - thieme-connect.com
The potential protective effects of arctigenin on 1-methyl-4-phenylpyridinium ion and 1-
methyl-4-phenyl-1, 2, 3, 6-tetrahydropyride-induced neurotoxicity were examined, and the …

Polyphenols from Toona sinensis seeds alleviate neuroinflammation in rats with Parkinson's disease via inhibiting p38MAPK signaling pathway

W Zhuang, C Chen, Y Ma, L Song, E Lyu… - Xi bao yu fen zi Mian yi …, 2019 - europepmc.org
Objective To explore the inhibitory effects of polyphenols from Toona sinensis seeds (PTSS)
on neuroinflammation and the underlying mechanism in rats with Parkinson's disease (PD) …

Protective effect of a novel herbmedicine, Hepad, on apoptosis of SH-SY5Y cells and a rat model of Parkinson's disease

SY Baek, NR Lee, DH Kim, A Gu, SY Kim… - Molecular & Cellular …, 2015 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder characterized by loss of
dopaminergic neurons in the substantia nigra pars compacta. In this study, we investigated …

Protective effects of Gynostemma pentaphyllum polysaccharides on PC12 cells impaired by MPP+

Q Deng, X Yang - International Journal of Biological Macromolecules, 2014 - Elsevier
The aim of the present study was to explore the neuroprotective effects of Gynostemma
pentaphyllum polysaccharides (GP) in a 1-methyl-4-phenylpyridiniumion (MPP+)-induced …

Neuroprotective effect of acteoside against MPTP-induced mouse model of Parkinsons disease

L Zhao, X PU - Chinese Pharmacological Bulletin, 1987 - pesquisa.bvsalud.org
Aim To study the neuroprotective effect of Acteoside against MPTP-induced mouse model of
Parkinsons disease (PD) and its mechanism. Methods The behavioral testing of C57 mice …

miR-126-5p targets SP1 to inhibit the progression of Parkinson's disease

YP Han, ZJ Liu, HH Bao, Q Wang, LL Su - European Neurology, 2022 - karger.com
Background: At present, symptomatic treatment may improve the life quality of Parkinson's
disease (PD) patients to a certain extent but cannot completely cure PD. Therefore, it is …

Tilianin attenuates MPP+‑induced oxidative stress and apoptosis of dopaminergic neurons in a cellular model of Parkinson's disease

J Li, S Xu - Experimental and Therapeutic Medicine, 2022 - spandidos-publications.com
The flavonoid tilianin is derived from the leaves of Dracocephalum moldavica L. amiales and
has been proven to serve a neuroprotective role in cerebral ischemia. Therefore, the aim of …

Protective effect of ginsenoside Rg1 on MPP+-induced apoptosis in SHSY5Y cells

XC Chen, F Fang, YG Zhu, LM Chen, YC Zhou… - Journal of neural …, 2003 - Springer
The neuroprotective mechanism of Rg1 was studied in this paper by means of its obvious
anti-apoptotic effect on human SHSY5Y cells. SHSY5Y cells were treated with MPP+ (1 …