In vivo Cell Tracking Using Non-invasive Imaging of Iron Oxide-Based Particles with Particular Relevance for Stem Cell-Based Treatments of Neurological and …

JC Glover, M Aswendt, JL Boulland, J Lojk… - Molecular imaging and …, 2020 - Springer
Stem cell-based therapeutics is a rapidly developing field associated with a number of
clinical challenges. One such challenge lies in the implementation of methods to track stem …

Labeling stem cells with superparamagnetic iron oxide nanoparticles: analysis of the labeling efficacy by microscopy and magnetic resonance imaging

Jasmin, ALM Torres, L Jelicks… - Nanoparticles in Biology …, 2012 - Springer
Stem cell therapy has emerged as a potential therapeutic option for cell death-related heart
diseases. Application of non-invasive cell tracking approaches is necessary to determine …

Evaluation of intracellular labeling with micron-sized particles of iron oxide (MPIOs) as a general tool for in vitro and in vivo tracking of human stem and progenitor …

JL Boulland, DSY Leung, M Thuen… - Cell …, 2012 - journals.sagepub.com
Magnetic resonance imaging (MRI)-based tracking is increasingly attracting attention as a
means of better understanding stem cell dynamics in vivo. Intracellular labeling with …

Iron oxide labeling does not affect differentiation potential of human bone marrow mesenchymal stem cells exhibited by their differentiation into cardiac and neuronal …

S Mohanty, KG Jain, SB Nandy, A Kakkar… - Molecular and cellular …, 2018 - Springer
Mesenchymal stem cells (MSCs) have shown promising outcomes in cardiac and neuronal
diseases. Efficient and noninvasive tracking of MSCs is essential to harness their …

Labeling hESCs and hMSCs with iron oxide nanoparticles for non-invasive in vivo tracking with MR imaging

TD Henning, S Boddington… - JoVE (Journal of Visualized …, 2008 - jove.com
In recent years, stem cell research has led to a better understanding of developmental
biology, various diseases and its potential impact on regenerative medicine. A non-invasive …

In vivo mononuclear cell tracking using superparamagnetic particles of iron oxide: feasibility and safety in humans

JMJ Richards, CA Shaw, NN Lang… - Circulation …, 2012 - Am Heart Assoc
Background—Cell therapy is an emerging and exciting novel treatment option for
cardiovascular disease that relies on the delivery of functional cells to their target site …

Tracking and quantification of magnetically labeled stem cells using magnetic resonance imaging

FT Goodfellow, GA Simchick… - Advanced functional …, 2016 - Wiley Online Library
Stem cell based therapies have critical impacts on treatments and cures of diseases such as
neurodegenerative or cardiovascular disease. In vivo tracking of stem cells labeled with …

Superparamagnetic iron oxide labeling of stem cells for MRI tracking and delivery in cardiovascular disease

DA Kedziorek, DL Kraitchman - Stem Cells for Myocardial Regeneration …, 2010 - Springer
In the mid-1980s, iron oxide nanoparticles were developed as contrast agents for diagnostic
imaging. In the last two decades, established methods to label cells with superparamagnetic …

Tracking stem cells with superparamagnetic iron oxide nanoparticles: perspectives and considerations

Jasmin, GT de Souza, RA Louzada… - International journal …, 2017 - Taylor & Francis
Superparamagnetic iron oxide nanoparticles (SPIONs) have been used for diagnoses in
biomedical applications, due to their unique properties and their apparent safety for humans …

[HTML][HTML] Superparamagnetic iron oxide nanoparticles function as a long-term, multi-modal imaging label for non-invasive tracking of implanted progenitor cells

CA Pacak, PE Hammer, AA MacKay, RP Dowd… - PLoS …, 2014 - journals.plos.org
The purpose of this study was to determine the ability of superparamagnetic iron oxide
(SPIO) nanoparticles to function as a long-term tracking label for multi-modal imaging of …