Self‐assembled adult adipose‐derived stem cell spheroids combined with biomaterials promote wound healing in a rat skin repair model

S Hsu, PS Hsieh - Wound Repair and Regeneration, 2015 - Wiley Online Library
Adult adipose‐derived stem cells (ASC s) are a type of multipotent mesenchymal stem cells
(MSC s) with easy availability and serve as a potential cell source for cell‐based therapy …

An injectable non-cross-linked hyaluronic-acid gel containing therapeutic spheroids of human adipose-derived stem cells

J Feng, K Mineda, SH Wu, T Mashiko, K Doi, S Kuno… - Scientific Reports, 2017 - nature.com
For chronic wounds, the delivery of stem cells in spheroidal structures can enhance graft
survival and stem cell potency. We describe an easy method for the 3D culture of adipose …

Locally administered adipose-derived stem cells accelerate wound healing through differentiation and vasculogenesis

C Nie, D Yang, J Xu, Z Si, X Jin… - Cell …, 2011 - journals.sagepub.com
Despite advances in wound closure techniques and devices, there is still a critical need for
new methods of enhancing the healing process to achieve optimal outcomes. Recently …

Cell sheet composed of adipose-derived stem cells demonstrates enhanced skin wound healing with reduced scar formation

J Yu, MY Wang, HC Tai, NC Cheng - Acta biomaterialia, 2018 - Elsevier
Scar formation remains a major clinical concern following tissue injuries such as skin
wounds. Adipose-derived stem cell (ASC) sheets can be fabricated quickly through …

Enhanced cellular engraftment of adipose-derived mesenchymal stem cell spheroids by using nanosheets as scaffolds

H Nagano, Y Suematsu, M Takuma, S Aoki, A Satoh… - Scientific reports, 2021 - nature.com
The short survival time of transplanted adipose-derived mesenchymal stem cells (ASCs) is a
problem for skin wound healing. Transplantation after the formation of cellular spheroids has …

The effect of adipose‐derived stem cells on wound healing: Comparison of methods of application

H Kim, MR Hyun, SW Kim - Stem cells international, 2019 - Wiley Online Library
Impaired wound healing is a significant medical problem. Recently, cell‐based therapy
focused on stem cells has been developed to overcome the challenges of defective wound …

Short-term spheroid formation enhances the regenerative capacity of adipose-derived stem cells by promoting stemness, angiogenesis, and chemotaxis

NC Cheng, SY Chen, JR Li… - Stem Cells Translational …, 2013 - academic.oup.com
Adipose-derived stem cells (ASCs) represent an important source of mesenchymal stem
cells for clinical application. During in vitro culture, ASCs quickly lose the expression of …

Effects of adipose-derived stem cells and their conditioned medium in a human ex vivo wound model

X Guo, C Schaudinn, U Blume-Peytavi, A Vogt… - Cells, 2022 - mdpi.com
Adult stem cells have been extensively investigated for tissue repair therapies. Adipose-
derived stem cells (ASCs) were shown to improve wound healing by promoting re …

Microvesicles from human adipose stem cells promote wound healing by optimizing cellular functions via AKT and ERK signaling pathways

S Ren, J Chen, D Duscher, Y Liu, G Guo… - Stem Cell Research & …, 2019 - Springer
Background Human adipose stem cells (ASCs) have emerged as a promising treatment
paradigm for skin wounds. Recent works demonstrate that the therapeutic effect of stem cells …

Intradermal injection of human adipose-derived stem cells accelerates skin wound healing in nude mice

J Rodriguez, F Boucher, C Lequeux… - Stem Cell Research & …, 2015 - Springer
Background The use of stem cells from adipose tissue or adipose-derived stem cells (ASCs)
in regenerative medicine could be an interesting alternative to bone marrow stem cells …