A new player in environmentally induced oxidative stress: polychlorinated biphenyl congener, 3, 3′-dichlorobiphenyl (PCB11)

Y Zhu, KA Mapuskar, RF Marek, W Xu… - toxicological …, 2013 - academic.oup.com
Recent analysis of air samples from Chicago and Lake Michigan areas observed a
ubiquitous airborne polychlorinated biphenyl (PCB) congener, 3, 3′-dichlorobiphenyl …

Elimination of PBB-153; findings from a cohort of Michigan adults

RB Hood, ML Terrell, AK Smith, S Curtis… - Environmental …, 2023 - Elsevier
Background An industrial accident led to the widespread contamination of polybrominated
biphenyl (PBB), a flame retardant, into the food system in Michigan in the 1970's. PBB …

[HTML][HTML] Particulate Air pollution mediated effects on insulin resistance in mice are independent of CCR2

C Liu, X Xu, Y Bai, J Zhong, A Wang, L Sun… - Particle and fibre …, 2017 - Springer
Background Chronic exposure to fine ambient particulate matter (PM 2.5) induces insulin
resistance. CC-chemokine receptor 2 (CCR2) appears to be essential in diet-induced insulin …

Metabolic remodeling of human skeletal myocytes by cocultured adipocytes depends on the lipolytic state of the system

JP Kovalik, D Slentz, RD Stevens, WE Kraus… - Diabetes, 2011 - Am Diabetes Assoc
OBJECTIVE Adipocyte infiltration of the musculoskeletal system is well recognized as a
hallmark of aging, obesity, and type 2 diabetes. Intermuscular adipocytes might serve as a …

Increased mitochondrial activity in BMP7-treated brown adipocytes, due to increased CPT1-and CD36-mediated fatty acid uptake

KL Townsend, D An, MD Lynes, TL Huang… - Antioxidants & redox …, 2013 - liebertpub.com
Aims: Brown adipose tissue dissipates chemical energy in the form of heat and regulates
triglyceride and glucose metabolism in the body. Factors that regulate fatty acid uptake and …

Impact of combined chronic exposure to low-dose bisphenol A and fructose on serum adipocytokines and the energy target metabolome in white adipose tissue

X Liu, G Li, J Zhong, O Rang, G Ou… - Human & …, 2023 - journals.sagepub.com
Background: Adipose tissue is a dynamic endocrine organ that plays a key role in regulating
metabolic homeostasis. Previous studies confirmed that bisphenol A (BPA) or fructose can …

Induction of mitochondrial uncoupling enhances VEGF120 but reduces MCP-1 release in mature 3T3-L1 adipocytes: possible regulatory mechanism through …

K Miyokawa-Gorin, K Takahashi, K Handa… - Biochemical and …, 2012 - Elsevier
Although white adipocytes contain a larger number of mitochondria per cytoplasmic volume,
adipocyte mitochondrial uncoupling to reduce the efficiency of ATP production on cellular …

Assessing Metabolic Differences Associated with Exposure to Polybrominated Biphenyl and Polychlorinated Biphenyls in the Michigan PBB Registry

SS Hoffman, D Liang, RB Hood, Y Tan… - Environmental …, 2023 - ehp.niehs.nih.gov
Background: Polybrominated biphenyls (PBB) and polychlorinated biphenyls (PCB) are
persistent organic pollutants with potential endocrine-disrupting effects linked to adverse …

[HTML][HTML] A peripheral CB1R antagonist increases lipolysis, oxygen consumption rate, and markers of beiging in 3T3-L1 adipocytes similar to RIM, suggesting that …

RL Paszkiewicz, RN Bergman, RS Santos… - International journal of …, 2020 - mdpi.com
With the increased prevalence of obesity and related co-morbidities, such as type 2 diabetes
(T2D), worldwide, improvements in pharmacological treatments are necessary. The brain …

Comparison of pharmacokinetic interactions and physiologically based pharmacokinetic modeling of PCB 153 and PCB 126 in nonpregnant mice, lactating mice, and …

SK Lee, YC Ou, RSH Yang - Toxicological Sciences, 2002 - academic.oup.com
Polychlorinated biphenyls (PCBs) are ubiquitous environmental contaminants that can
induce neurological defects in infants and children via placental and lactational transfer. To …