Different subclasses and isotypes of antibodies against phosphorylcholine in haemodialysis patients: association with mortality

SK Samal, AR Qureshi, M Rahman… - Clinical & …, 2020 - academic.oup.com
The risk of premature death is high among patients on haemodialysis (HD patients). We
previously determined that immunoglobulin (Ig) M antibodies against phosphorylcholine …

Low levels of IgM antibodies against phosphorylcholine-A increase mortality risk in patients undergoing haemodialysis

JJ Carrero, X Hua, P Stenvinkel… - Nephrology Dialysis …, 2009 - academic.oup.com
Background. Atherosclerosis is an inflammatory disease where oxidized low-density
lipoprotein may play an important role through phosphorylcholine (PC)-exposing …

Low level natural antibodies against phosphorylcholine: a novel risk marker and potential mechanism in atherosclerosis and cardiovascular disease

J Frostegård - Clinical immunology, 2010 - Elsevier
Atherosclerosis is an inflammatory condition characterised by an abundance of activated
immunocompetent cells in plaques which cause cardiovascular disease (CVD) when they …

Long-term prognostic value of IgM antibodies against phosphorylcholine for adverse cardiovascular events in patients with stable coronary heart disease

A Imhof, W Koenig, A Jaensch, U Mons, H Brenner… - Atherosclerosis, 2015 - Elsevier
Abstract Background Low concentrations of IgM-phosphorylcholine autoantibodies (IgM-anti-
PC) have been shown to be associated with increased risk of incident cardiovascular …

Low levels of IgM antibodies to phosphorylcholine predict cardiovascular disease in 60-year old men: effects on uptake of oxidized LDL in macrophages as a potential …

U de Faire, J Su, X Hua, A Frostegård, M Halldin… - Journal of …, 2010 - Elsevier
OBJECTIVE: We here determine the role of IgM antibodies against phosphorylcholine (anti-
PC) in prediction of cardiovascular disease (CVD) and on macrophage uptake of Oxidized …

Antibodies against Phosphorylcholine—Implications for Chronic Inflammatory Diseases

J Frostegård - Metabolites, 2023 - mdpi.com
Atherosclerosis and its main consequence, cardiovascular disease (CVD) are nowadays
regarded as chronic inflammatory disease conditions, and CVD is the main cause of death …

Natural antibodies against phosphorylcholine in cardiovascular disease

U De Faire, J Frostegård - Annals of the New York Academy of …, 2009 - Wiley Online Library
Atherosclerosis is a chronic inflammatory disease characterized by the presence of activated
immune‐competent cells in the lesions, producing mainly proinflammatory cytokines …

Autoantibodies to phosphorylcholine and cardiovascular outcomes in patients with acute coronary syndromes in the ATLAS ACS-TIMI 46 trial

BJ Geller, JL Mega, DA Morrow, J Guo… - Journal of thrombosis …, 2014 - Springer
Atherogenesis is a complex inflammatory process stemming from the accumulation and
oxidation of low density lipoproteins (LDL). IgM autoantibodies against phosphorylcholine …

Immunoglobulin G1 antibodies against phosphorylcholine are associated with protection in systemic lupus erythematosus and atherosclerosis: potential underlying …

D Thiagarajan, R Fiskesund, A Frostegård… - ACR open …, 2020 - Wiley Online Library
Objective Immunoglobulin M antibodies against phosphorylcholine (anti‐PC s) may be
protective in atherosclerosis, cardiovascular disease (CVD), and systemic lupus …

Low levels of IgM antibodies against phosphorylcholine predict development of acute myocardial infarction in a population-based cohort from northern Sweden

H Grönlund, G Hallmans, JH Jansson… - European Journal of …, 2009 - academic.oup.com
Objective Phosphorylcholine (PC) is one important epitope on oxidized low-density
lipoprotein that may play an important role by contributing to the atherogenicity of oxidized …