[HTML][HTML] Polyclonal free light chains in IgA-nephropathy: correlation with clinical and morphological parameters and prognostic significance

AA Churko, MS Khrabrova… - Nephrology (Saint …, 2021 - journal.nephrolog.ru
BACKGROUND. Mechanisms of the initiation of renal interstitial inflammation and fibrosis
caused by immunoglobulin monoclonal free light chains (mFLC) in monoclonal …

Antiphospholipid antibodies and renal involvement

A Gigante, ML Gasperini, R Cianci, B Barbano… - American Journal of …, 2009 - karger.com
Antiphospholipid antibodies are a heterogeneous group of autoantibodies associated with
the hypercoagulable state affecting all vascular districts with thrombosis named …

Complement in the pathophysiology of the antiphospholipid syndrome

S Chaturvedi, RA Brodsky, KR McCrae - Frontiers in immunology, 2019 - frontiersin.org
The antiphospholipid syndrome (APS) is characterized by thrombosis and pregnancy
morbidity in the presence of antiphospholipid antibodies (aPL). Complement is a system of …

Antiphospholipid syndrome: the need for new international classification criteria

G El Hasbani, AT Taher, S Sciascia… - Expert Review of …, 2021 - Taylor & Francis
Introduction: As soon as the association of lupus anticoagulant (LAC) and anticardiolipin
antibodies (aCL) with thrombosis and miscarriages was described in the 1980s, the …

End-stage renal disease from glomerulonephritis associated with anti-phospholipid syndrome

L Butani - Pediatric Nephrology, 2004 - Springer
Primary anti-phospholipid syndrome (APS) is perceived to be an uncommon disorder,
infrequently recognized as a cause of renal disease in childhood. While renal involvement in …

Histological antiphospholipid-associated nephropathy versus lupus nephritis in patients with systemic lupus erythematosus: an observational cross-sectional study …

J Gerhardsson, B Sundelin, A Zickert… - Arthritis research & …, 2015 - Springer
Introduction Renal involvement is a severe complication in systemic lupus erythematosus
(SLE). Moreover, a subset of SLE patients develop the anti-phospholipid syndrome (APS) …

Immunogenicity of therapeutic proteins

H Schellekens - Nephrology Dialysis Transplantation, 2003 - academic.oup.com
A year ago Nicole Casadevall of the Hotel-Dieu in Paris and her colleagues published their
first 13 cases of pure red-cell aplasia (PRCA) associated with the use of erythropoietin (Epo) …

Contribution of polyclonal free light chain deposition to tubular injury

R Parasuraman, SC Wolforth, WN Wiesend… - American Journal of …, 2014 - karger.com
Introduction: Excretion of monoclonal free light chains (MFLC) beyond the renal threshold
can cause kidney injury, but evidence for polyclonal free light chains (PFLC)-mediated injury …

Peroxidasin is a novel target of autoantibodies in lupus nephritis

P Manral, S Colon, G Bhave, MH Zhao, S Jain… - Kidney International …, 2019 - kireports.org
Results Sera from 32 patients with biopsy-confirmed proliferative or membranous LN
(ISN/RPS class III, IV, or V) were analyzed for peroxidasin immunoreactivity by enzyme …

Immunosenescence and Immune Exhaustion Are Associated with Levels of Protein-Bound Uremic Toxins in Patients on Hemodialysis

T Tourountzis, G Lioulios, S Van Laecke… - Biomedicines, 2023 - mdpi.com
Background: The accumulation of protein-bound uremic toxins (PBUTs) in chronic kidney
disease may affect patients' immune status. The aim of the study was to evaluate their …