αvβ3 integrin is a marker of tumor neoangiogenesis that specifically binds to RGD
containing peptides. Hence, the present study is focused on the development of 99mTc …

Background: Labeled RGD peptide that specifically targets ανβ3 integrin has great potential
for the early diagnosis of malignant tumors. αvβ3 integrin receptors appear specifically more …

As the most common malignant brain tumors, glioblastoma multiforme (GBM) was
characterized by angiogenesis and tumor cells proliferation. Dual targeting to …

The integrin family of cell adhesion receptors regulates a diverse array of cellular functions
crucial to the initiation, progression and metastasis of solid tumours. The importance of …

Integrin αvβ3 plays a critical role in tumor angiogenesis and metastasis. Radiolabeled RGD
peptides that are integrin αvβ3-specific are very useful for noninvasive imaging of integrin …

Simple Summary Glioblastoma (GB) is the most common and most deadly form of brain
tumor in adults which currently lacks effective treatments. Thus, there is a high need to …

In this paper, using a hybrid small-animal Micro SPECT/CT imaging system, we report that a
new 125I-Cilengitide-like RGD-cyclopentapeptide, containing d-morpholine-3-carboxylic …

αVβ3 Integrins are a widely recognized target for in vivo molecular imaging of pathological
conditions such as inflammation, cancer and rheumatoid arthritis. We have evaluated the …

Glioblastoma, one of the most aggressive forms of brain cancer, is featured by high tumor
cell motility and invasiveness, which not only fuel tumor infiltration, but also enable escape …

Abstract Purpose Radiolabeled Arg-Gly-Asp (RGD) and Ala-Thr-Trp-Leu-Pro-Pro-Arg
(ATWLPPR) peptide analogs have received interests for their capability to serve as …