Objective: To verify incidence rates and their temporal trend in a homogeneous, ethnically,
and genetically distinct population of central Sardinia (the Nuoro province). Background …

Twenty years after a first survey, a follow-up study was performed on the prevalence of MS in
Enna (Sicily), southern Italy. The prevalence of definite MS rose from 53 to 120.2 per …

Objective: To estimate the presence of familial aggregation and determine the contribution of
genetic factors to familial clustering of MS in patients coming from Sardinia, a Mediterranean …

Objective: An epidemiologic survey was conducted to determine the prevalence and
incidence of MS in the city of Catania, Sicily, Italy. Prevalence rate was calculated as point …

Intensive search of all cases of MS occurring in the Sardinian commune of Macomer since
1912 indicated that MS was absent up to the early 1950s. All 13 ascertained cases had …

Italy is currently regarded as a medium-frequency area for MS. In recent years, however, this
opinion has been questioned by many. Current public health organization in Italy is …

The Sardinians are an ethnically homogeneous population, having a genetic structure quite
different from that of all other Italian and European populations. All epidemiological studies …

Objectives–To update prevalence and incidence rates of MS among Sardinians. Materials
and methods–The present work is a “spider” kind of population based survey, conducted …

Prevalence studies carried out in Sardinia from 1975 suggest an increasing occurrence of
MS. However, it is questionable whether this increase represents a real change in MS …

Sardinia is a high-risk area for multiple sclerosis (MS), with prevalence rates of 150 per
100,000 population. The study included 689 MS patients (female-male ratio 2.6) with …