Left ventricular remodelling post-myocardial infarction: pathophysiology, imaging, and novel therapies

S Frantz, MJ Hundertmark… - European heart …, 2022 - academic.oup.com
Most patients survive acute myocardial infarction (MI). Yet this encouraging development
has certain drawbacks: heart failure (HF) prevalence is increasing and patients affected tend …

[HTML][HTML] Left ventricular remodeling after myocardial infarction: from physiopathology to treatment

SA Leancă, D Crișu, AO Petriș, I Afrăsânie, A Genes… - Life, 2022 - mdpi.com
Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

[HTML][HTML] Postinfarct left ventricular remodelling: a prevailing cause of heart failure

A Galli, F Lombardi - Cardiology research and practice, 2016 - hindawi.com
Heart failure is a chronic disease with high morbidity and mortality, which represents a
growing challenge in medicine. A major risk factor for heart failure with reduced ejection …

Mechanisms of postinfarct left ventricular remodeling

BA French, CM Kramer - Drug Discovery Today: Disease Mechanisms, 2007 - Elsevier
Heart failure secondary to myocardial infarction (MI) remains a major source of morbidity
and mortality. Long-term outcome after MI can be largely be defined in terms of its impact on …

Potential novel pharmacological therapies for myocardial remodelling

U Landmesser, KC Wollert, H Drexler - Cardiovascular research, 2009 - academic.oup.com
Left ventricular (LV) remodelling remains an important treatment target in patients after
myocardial infarction (MI) and chronic heart failure (CHF). Accumulating evidence has …

Adverse remodeling and reverse remodeling after myocardial infarction

AS Bhatt, AP Ambrosy, EJ Velazquez - Current cardiology reports, 2017 - Springer
Abstract Purpose of Review The purpose of this review it to summarize the current literature
on remodeling after myocardial infarction, inclusive of pathophysiological considerations …

Postinfarction left ventricular remodelling: where are the theories and trials leading us?

ZR Yousef, SR Redwood, MS Marber - Heart, 2000 - heart.bmj.com
While mortality from overt ischaemic heart disease is falling, that from heart failure is
increasing and reaching epidemic proportions. 1 Although an aging population is partly …

Left ventricular post-infarct remodeling: implications for systolic function improvement and outcomes in the modern era

P van der Bijl, R Abou, L Goedemans, BJ Gersh… - Heart Failure, 2020 - jacc.org
Objectives This study sought to investigate the impact of post-infarct left ventricular (LV)
remodeling on outcomes in the contemporary era. Background LV remodeling after ST …

[HTML][HTML] Pharmacological modulation of cardiac remodeling after myocardial infarction

W Zhao, J Zhao, J Rong - Oxidative Medicine and Cellular Longevity, 2020 - hindawi.com
Cardiac remodeling describes a series of structural and functional changes in the heart after
myocardial infarction (MI). Adverse post-MI cardiac remodeling directly jeopardizes the …

Left ventricular remodeling in the post-infarction heart: a review of cellular, molecular mechanisms, and therapeutic modalities

JJ Gajarsa, RA Kloner - Heart failure reviews, 2011 - Springer
As more patients survive myocardial infarctions, the incidence of heart failure increases.
After an infarction, the human heart undergoes a series of structural changes, which are …