Myocardial infarction and subsequent heart failure is a major health burden associated with
significant mortality and morbidity in western societies. The ability of cardiac tissue to …

In patients with heart failure, the beneficial effects of drug and device therapies counteract to
some extent ongoing cardiac damage. According to the net balance between these two …

Cardiac remodelling refers to changes in left ventricular structure and function over time,
with a progressive deterioration that may lead to heart failure (HF) development (adverse …

This review briefly highlights the major mechanisms of left ventricular (LV) remodeling
following myocardial infarction in heart failure and presents novel strategies to limit infarct …

Ventricular remodeling after myocardial infarction is defined as progressive chamber dilation
and wall thinning, which leads to functional compromise. Remodeling is mediated by active …

Due to continuous remodelling myocardial dysfunction is a progressive condition. Even if the
initial event is so mild that it causes no immediate cardiac dysfunction (eg a small …

Ventricular remodeling, first described in animal models of left ventricular (LV) stress and
injury, occurs progressively in untreated patients after large myocardial infarction and in …

Cardiac remodelling is classified as physiological (in response to growth, exercise and
pregnancy) or pathological (in response to inflammation, ischaemia, ischaemia/reperfusion …

ST-segment elevation myocardial infarction (STEMI) remains a significant source of
morbidity and mortality worldwide. Despite advances in treatment leading to a significant …

Objective To describe the time course of myocardial infarct (MI) healing and left ventricular
(LV) remodelling and to assess factors predicting LV remodelling using cardiac MRI …