A prodrome is considered an early set of signs or symptoms indicating the onset of a
disease or illness. In multiple sclerosis (MS), the prodromal period is the months or years …

A prodrome is an early set of signs, symptoms or other findings that occur before the onset of
typical symptoms of a disease. Prodromal phases are well recognized in several …

A growing body of work points toward the existence of a clinically symptomatic prodromal
phase in multiple sclerosis (MS) that might span 5–10 years or more. A prodrome is an early …

A prodrome is an early set of signs or symptoms that indicate the onset of a disease before
more typical symptoms develop. Prodromal stages are well recognized in some neurological …

Introduction The identification of a prodromal phase in multiple sclerosis (MS) could have
major implications for earlier recognition and management of MS. The authors conducted a …

Typically, the clinical course of multiple sclerosis is characterized by episodes, from which
recovery may occur, and by progression. These phases usually evolve in sequence as part …

Background and purpose The multiple sclerosis prodrome remains poorly understood. We
aimed to examine the prodrome in people with relapsing remitting multiple sclerosis at onset …

Objectives To investigate the relationship among attacks in the first 2 years (early relapses),
secondary progression (SP), and late disability in multiple sclerosis (MS). Design Cohort …

Background: The multiple sclerosis (MS) prodrome is poorly characterized. Objective: To
phenotype the MS prodrome via health care encounters. Methods: Using data from a …

Background: It is unclear if all patients with relapsing–remitting multiple sclerosis (RRMS)
ultimately develop progressive MS. Onset of progressive disease course seems to be age …