[HTML][HTML] Aggressive prolactinoma

A Valea, F Sandru, A Petca… - Experimental and …, 2022 - spandidos-publications.com
Aggressive prolactinoma (APRL) is a subgroup of aggressive pituitary tumors (accounting
for 10% of all hypophyseal neoplasia) which are defined by: invasion based on radiological …

[HTML][HTML] Update in pathogenesis, diagnosis, and therapy of prolactinoma

N Fukuhara, M Nishiyama, Y Iwasaki - Cancers, 2022 - mdpi.com
Simple Summary This review updates recent advances in the pathogenesis, diagnosis, and
therapy of prolactinoma. Prolactinomas, comprising 30–50% of all pituitary neuroendocrine …

[HTML][HTML] Treatment strategies for dopamine agonist-resistant and aggressive prolactinomas: a comprehensive analysis of the literature

R Sari, MA Altinoz, EBK Ozlu, A Sav… - Hormone and …, 2021 - thieme-connect.com
Despite most of the prolactinomas can be treated with endocrine therapy and/or surgery, a
significant percentage of these tumors can be resistant to endocrine treatments and/or recur …

[HTML][HTML] Therapeutic response to pazopanib: case report and literature review on molecular abnormalities of aggressive prolactinomas

EJ Medina, YM Zohdy, E Porto… - Frontiers in …, 2023 - frontiersin.org
Introduction Aggressive prolactinomas (APRLs) pose a significant clinical challenge due to
their high rate of regrowth and potentially life-threatening complications. In this study, we …

[PDF][PDF] Prolactinoma: clinical characteristics, management and outcome

H Irfan, W Shafiq, AI Siddiqi, S Ashfaq, S Attaullah… - Cureus, 2022 - cureus.com
Aim Prolactinoma, a prolactin (PRL) secreting functioning pituitary tumor, is the most
common of all pituitary adenomas (PA) accounting for 40-60% and dopamine agonists (DA) …

[HTML][HTML] The PRolaCT studies—a study protocol for a combined randomised clinical trial and observational cohort study design in prolactinoma

IM Zandbergen, AH Zamanipoor Najafabadi… - Trials, 2021 - Springer
Background First-line treatment for prolactinomas is a medical treatment with dopamine
agonists (DAs), which effectively control hyperprolactinaemia in most patients, although post …

When to discontinue treatment of prolactinoma?

JAH Wass - Nature Clinical Practice Endocrinology & Metabolism, 2006 - nature.com
Prolactinomas are the most common hormone-secreting pituitary tumors. Treatment with
dopamine agonists can stabilize disease and recent evidence suggests that in many cases …

[HTML][HTML] Prolactinoma

RKR Yatavelli, K Bhusal - 2017 - europepmc.org
Objectives: Identify the common presentations of prolactinomas. Outline the evaluation of
prolactinomas. Review the management of prolactinomas. Explain the role of collaboration …

[HTML][HTML] Treatment of prolactinoma

WJ Inder, C Jang - Medicina, 2022 - mdpi.com
Prolactinomas are the commonest form of pituitary neuroendocrine tumor (PitNET),
representing approximately half of such tumors. Dopamine agonists (DAs) have traditionally …

What causes a prolactinoma to be aggressive or to become a pituitary carcinoma?

J Phillips, HE East, SE French, E Melcescu… - Hormones, 2012 - Springer
INTRODUCTION Malignant prolactinoma is an exceedingly rare endocrine tumor and
cannot be diagnosed on histological grounds alone. Similarly to other neuroendocrine …