[HTML][HTML] Genetic and epigenetic studies in diabetic kidney disease

HF Gu - Frontiers in genetics, 2019 - frontiersin.org
Chronic kidney disease is a worldwide health crisis, while diabetic kidney disease (DKD)
has become the leading cause of end-stage renal disease (ESRD). DKD is a microvascular …

[HTML][HTML] Beyond genetics: epigenetic code in chronic kidney disease

RS Dwivedi, JG Herman, TA McCaffrey, DSC Raj - Kidney international, 2011 - Elsevier
Epigenetics refers to a heritable change in the pattern of gene expression that is mediated
by a mechanism specifically not due to alterations in the primary nucleotide sequence. Well …

[HTML][HTML] Diabetic kidney diseases revisited: A new perspective for a new era

H Fu, S Liu, SI Bastacky, X Wang, XJ Tian, D Zhou - Molecular metabolism, 2019 - Elsevier
Background Globally, diabetic kidney disease (DKD) is the leading cause of end-stage renal
disease. As the most common microvascular complication of diabetes, DKD is a thorny …

Epigenetic regulations in diabetic nephropathy

Z Lu, N Liu, F Wang - Journal of diabetes research, 2017 - Wiley Online Library
Diabetic nephropathy (DN) is a chronic complication of diabetes and the most common
cause of end‐stage kidney disease. It has been reported that multiple factors are involved in …

Diabetic nephropathy—emerging epigenetic mechanisms

M Kato, R Natarajan - Nature Reviews Nephrology, 2014 - nature.com
Diabetic nephropathy (DN), a severe microvascular complication frequently associated with
both type 1 and type 2 diabetes mellitus, is a leading cause of renal failure. The condition …

[HTML][HTML] Recent developments in epigenetics of acute and chronic kidney diseases

MA Reddy, R Natarajan - Kidney international, 2015 - Elsevier
The growing epidemic of obesity and diabetes, the aging population as well as prevalence
of drug abuse has led to significant increases in the rates of the closely associated acute …

Pathophysiologic mechanisms in diabetic kidney disease: A focus on current and future therapeutic targets

J Barrera‐Chimal, F Jaisser - Diabetes, Obesity and …, 2020 - Wiley Online Library
Diabetic kidney disease (DKD) is the primary cause of chronic kidney disease around the
globe and is one of the main complications in patients with type 1 and 2 diabetes. The …

A genome-wide association study of diabetic kidney disease in subjects with type 2 diabetes

NR Van Zuydam, E Ahlqvist, N Sandholm… - Diabetes, 2018 - Am Diabetes Assoc
Identification of sequence variants robustly associated with predisposition to diabetic kidney
disease (DKD) has the potential to provide insights into the pathophysiological mechanisms …

[HTML][HTML] Epigenetics in the pathogenesis of diabetic nephropathy: Epigenetics in the pathogenesis of diabetic nephropathy

X Li, L Lu, W Hou, T Huang, X Chen, J Qi… - Acta Biochimica et …, 2022 - ncbi.nlm.nih.gov
Diabetic nephropathy (DN), which is a common microvascular complication with a high
incidence in diabetic patients, greatly increases the mortality of patients. With further study …

[HTML][HTML] Epigenetics in diabetic nephropathy, immunity and metabolism

ST Keating, JA van Diepen, NP Riksen, A El-Osta - Diabetologia, 2018 - Springer
When it comes to the epigenome, there is a fine line between clarity and confusion—walk
that line and you will discover another fascinating level of transcription control. With the …