Diabetic kidney disease (DKD) is the most common etiology of chronic kidney disease
(CKD) in the industrialized world and accounts for much of the excess mortality in patients …

Diabetic kidney disease (DKD) is the leading cause of kidney failure worldwide and the
single strongest predictor of mortality in patients with diabetes. DKD is a prototypical disease …

We identified potential epigenetic biomarkers for chronic kidney disease progression by
comparing site-specific DNA methylation levels in more than 14,000 genes between African …

It is evident that metabolic memory, whereby diabetic complications continue to develop and
progress in individuals who returned to normal glycemic control after a period of transient …

The prevalence of diabetes and its related complications are increasing significantly
globally. Collected evidence suggested that several genetic and environmental factors …

Diabetes mellitus contributes greatly to morbidity, mortality, and overall health care costs. In
major part, these outcomes derive from the high incidence of progressive kidney dysfunction …

Abstract Between 20% and 40% of patients with diabetes ultimately develop diabetic
nephropathy, which in the US is the most common cause of end-stage renal disease …

There is growing evidence that epigenetic regulation of gene expression including post-
translational histone modifications (PTHMs), DNA methylation and microRNA (miRNA) …

There has been a rapid increase in the incidence of diabetes as well the associated
vascular complications. Both genetic and environmental factors have been implicated in …

Background: Diabetes mellitus (DM) poses a severe threat to global public health. Diabetic
nephropathy (DN) is one of the most common complications of diabetes and the leading …